ID   C2KUK0_9FIRM            Unreviewed;       239 AA.
AC   C2KUK0;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   SubName: Full=ThiF family protein {ECO:0000313|EMBL:EEJ52557.1};
GN   ORFNames=HMPREF6123_0169 {ECO:0000313|EMBL:EEJ52557.1};
OS   Oribacterium sinus F0268.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Oribacterium.
OX   NCBI_TaxID=585501 {ECO:0000313|EMBL:EEJ52557.1, ECO:0000313|Proteomes:UP000004121};
RN   [1] {ECO:0000313|EMBL:EEJ52557.1, ECO:0000313|Proteomes:UP000004121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0268 {ECO:0000313|EMBL:EEJ52557.1,
RC   ECO:0000313|Proteomes:UP000004121};
RA   Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA   Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA   Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA   Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA   Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA   Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA   Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA   Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA   Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA   Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEJ52557.1}.
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DR   EMBL; ACKX01000017; EEJ52557.1; -; Genomic_DNA.
DR   RefSeq; WP_007157704.1; NZ_GG668535.1.
DR   AlphaFoldDB; C2KUK0; -.
DR   STRING; 585501.HMPREF6123_0169; -.
DR   eggNOG; COG1179; Bacteria.
DR   HOGENOM; CLU_013325_4_1_9; -.
DR   InParanoid; C2KUK0; -.
DR   OrthoDB; 9804150at2; -.
DR   Proteomes; UP000004121; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   CDD; cd00755; YgdL_like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004121}.
FT   DOMAIN          10..238
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   239 AA;  26018 MW;  CA65952621FCD664 CRC64;
     MEGQFSRTER LLGSEAVEKL SKAKVIVFGI GGVGGYCVES LVRSGVGQID VVDDDVVCLS
     NLNRQIIATR DTVGRAKVEI AEERIHSINP DCKVRVFRCF YLPETKDQFD FSAYDYVVDA
     VDTVAAKLSL IEAAKEAGVP IISAMGAGNK LNPAGFKVAD LYETRICPLA KVMRRECKKR
     GIESLKVVYS EEMPRKPIEN AEEALPKAKG KRSVPGSVAF VPPVVGLIMG GEIIKDLLQ
//