ID   C2KW83_9FIRM            Unreviewed;       260 AA.
AC   C2KW83;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=RNA methyltransferase, TrmH family {ECO:0000313|EMBL:EEJ51970.1};
GN   ORFNames=HMPREF6123_0758 {ECO:0000313|EMBL:EEJ51970.1};
OS   Oribacterium sinus F0268.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Oribacterium.
OX   NCBI_TaxID=585501 {ECO:0000313|EMBL:EEJ51970.1, ECO:0000313|Proteomes:UP000004121};
RN   [1] {ECO:0000313|EMBL:EEJ51970.1, ECO:0000313|Proteomes:UP000004121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0268 {ECO:0000313|EMBL:EEJ51970.1,
RC   ECO:0000313|Proteomes:UP000004121};
RA   Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA   Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA   Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA   Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA   Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA   Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA   Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA   Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA   Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA   Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEJ51970.1}.
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DR   EMBL; ACKX01000079; EEJ51970.1; -; Genomic_DNA.
DR   AlphaFoldDB; C2KW83; -.
DR   STRING; 585501.HMPREF6123_0758; -.
DR   eggNOG; COG0566; Bacteria.
DR   HOGENOM; CLU_021322_3_2_9; -.
DR   InParanoid; C2KW83; -.
DR   OrthoDB; 9794400at2; -.
DR   Proteomes; UP000004121; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR43191:SF16; RNA METHYLASE-RELATED; 1.
DR   PANTHER; PTHR43191; RRNA METHYLTRANSFERASE 3; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
DR   SUPFAM; SSF55315; L30e-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EEJ51970.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004121};
KW   Transferase {ECO:0000313|EMBL:EEJ51970.1}.
FT   DOMAIN          107..247
FT                   /note="tRNA/rRNA methyltransferase SpoU type"
FT                   /evidence="ECO:0000259|Pfam:PF00588"
SQ   SEQUENCE   260 AA;  29058 MW;  B817118C1AE8C56F CRC64;
     MHRIESPHNE GLKEIRELTK KAKKRWEKGM FVAEGERLLL DLPASSLLQL YVQEDYKGAL
     PRGIEKEDSR ICILSKKAME SISTTEHGQG ILGLLRFPKK EKPKGDLFLI LENIQDPGNL
     GTLFRTAEAA GVNHIFLSRN TVDPFSPKVV RSTMGSLFRL PFSIEEDLFF LCESLKSAGV
     QVFALDLDGK KTHFQAAFQG PSAFLFGNEG NGLTKELSQC ATEKLLIPME GKIESLNVAT
     SASIVLYEAV RQRRYIKEEG
//