ID C2NLA6_BACCE Unreviewed; 74 AA.
AC C2NLA6;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=RNA-binding protein Hfq {ECO:0000256|HAMAP-Rule:MF_00436};
GN Name=hfq {ECO:0000256|HAMAP-Rule:MF_00436};
GN ORFNames=bcere0004_34880 {ECO:0000313|EMBL:EEK55141.1};
OS Bacillus cereus BGSC 6E1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=526970 {ECO:0000313|EMBL:EEK55141.1};
RN [1] {ECO:0000313|EMBL:EEK55141.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGSC 6E1 {ECO:0000313|EMBL:EEK55141.1};
RX PubMed=22645259; DOI=10.1101/gr.134437.111;
RA Zwick M.E., Joseph S.J., Didelot X., Chen P.E., Bishop-Lilly K.A.,
RA Stewart A.C., Willner K., Nolan N., Lentz S., Thomason M.K.,
RA Sozhamannan S., Mateczun A.J., Du L., Read T.D.;
RT "Genomic characterization of the Bacillus cereus sensu lato species:
RT Backdrop to the evolution of Bacillus anthracis.";
RL Genome Res. 22:1512-1524(2012).
CC -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC mRNAs to facilitate mRNA translational regulation in response to
CC envelope stress, environmental stress and changes in metabolite
CC concentrations. Also binds with high specificity to tRNAs.
CC {ECO:0000256|HAMAP-Rule:MF_00436}.
CC -!- SUBUNIT: Homohexamer. {ECO:0000256|HAMAP-Rule:MF_00436}.
CC -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000256|HAMAP-
CC Rule:MF_00436}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEK55141.1}.
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DR EMBL; ACLU01000084; EEK55141.1; -; Genomic_DNA.
DR RefSeq; WP_000813896.1; NZ_CM000716.1.
DR AlphaFoldDB; C2NLA6; -.
DR SMR; C2NLA6; -.
DR GeneID; 84226241; -.
DR HOGENOM; CLU_113688_3_0_9; -.
DR Proteomes; UP000000284; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01716; Hfq; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR HAMAP; MF_00436; Hfq; 1.
DR InterPro; IPR005001; Hfq.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR047575; Sm.
DR NCBIfam; TIGR02383; Hfq; 1.
DR PANTHER; PTHR34772; RNA-BINDING PROTEIN HFQ; 1.
DR PANTHER; PTHR34772:SF1; RNA-BINDING PROTEIN HFQ; 1.
DR Pfam; PF17209; Hfq; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS52002; SM; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00436};
KW Stress response {ECO:0000256|ARBA:ARBA00023016, ECO:0000256|HAMAP-
KW Rule:MF_00436}.
FT DOMAIN 9..69
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
SQ SEQUENCE 74 AA; 8646 MW; 621400020EF87C50 CRC64;
MKQSINIQDQ FLNQLRKENT FVTLYLLNGF QLRGLIKGFD NFTVLLETEG KQQLIYKHAI
STFVPQKNVS IELE
//
