ID C3KAJ2_PSEFS Unreviewed; 497 AA.
AC C3KAJ2;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN Name=mmsA {ECO:0000313|EMBL:CAY46944.1};
GN OrderedLocusNames=PFLU_0676 {ECO:0000313|EMBL:CAY46944.1};
OS Pseudomonas fluorescens (strain SBW25).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216595 {ECO:0000313|EMBL:CAY46944.1};
RN [1] {ECO:0000313|EMBL:CAY46944.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAY46944.1};
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
RN [2] {ECO:0000313|EMBL:CAI2794987.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAI2794987.1};
RA Fortmann-Grote C.;
RL Submitted (OCT-2023) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; OV986001; CAI2794987.1; -; Genomic_DNA.
DR EMBL; AM181176; CAY46944.1; -; Genomic_DNA.
DR RefSeq; WP_012722054.1; NC_012660.1.
DR AlphaFoldDB; C3KAJ2; -.
DR STRING; 294.SRM1_00753; -.
DR PATRIC; fig|216595.4.peg.911; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_10_6; -.
DR OrthoDB; 9812625at2; -.
DR Proteomes; UP001152918; Chromosome.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:UniProtKB-EC.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CAY46944.1}.
FT DOMAIN 15..477
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 497 AA; 53369 MW; 97708C4A1E72D2DB CRC64;
MSLIQHLING ELVNDSGRSA DVYNPSTGQV IHQVPLASRE TIQQAIDSAK AAFPAWRNTP
PAKRAQVMFR FKQLLEQNEA RISQLISEEH GKTLEDAAGE LKRGIENVEY ACSAPEILKG
EYSRNVGPNI DAWSDFQPLG VVAGITPFNF PAMVPLWMYP LAIVCGNCFI LKPSERDPSS
TLLIAQLLQE AGLPKGVLSV VHGDKGAVDA LIEAPEVKAL SFVGSTPIAE YIYSEATKRG
KRVQALGGAK NHAVLMPDAD LDNAVSALMG AAYGSCGERC MAISVAVCVG DQVADALIAK
LVPQVKALKI GAGTSCGLDM GPLVTGQARD KVSGYIEDGV SSGAKLVVDG RGLSVAGHEE
GFFLGGSLFD HVTPEMRIYK EEIFGPVLCV VRVASLEAAM QLINDHEYGN GTCIFTRDGE
AARLFCDEIE VGMVGVNVPL PVPVAYHSFG GWKRSLFGDL HAYGPDGVRF YTRRKAITQR
WPQRASHEAS QFAFPSL
//
