ID C3LMP2_VIBCM Unreviewed; 386 AA.
AC C3LMP2;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN OrderedLocusNames=VCM66_1504 {ECO:0000313|EMBL:ACP05818.1};
OS Vibrio cholerae serotype O1 (strain M66-2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=579112 {ECO:0000313|EMBL:ACP05818.1, ECO:0000313|Proteomes:UP000001217};
RN [1] {ECO:0000313|EMBL:ACP05818.1, ECO:0000313|Proteomes:UP000001217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M66-2 {ECO:0000313|EMBL:ACP05818.1,
RC ECO:0000313|Proteomes:UP000001217};
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001233; ACP05818.1; -; Genomic_DNA.
DR AlphaFoldDB; C3LMP2; -.
DR KEGG; vcm:VCM66_1504; -.
DR HOGENOM; CLU_018816_14_1_6; -.
DR Proteomes; UP000001217; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR PANTHER; PTHR32347:SF19; RND EFFLUX PUMP MEMBRANE FUSION PROTEIN BARREL-SANDWICH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 55..266
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 114..167
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 386 AA; 41691 MW; 5065988238D85062 CRC64;
MIDEINEFFM AKRWTLLATL VGVGLAGGYY TLTYTPESSS PLPTLNVSRG TIEKQAVAVG
QIMPSHSVAI KSQINGIVGE IYVREGQHVE QGQPLIKVRP NPTPQALTDA STELMQSEAN
LESDLQRLAN LERLVKQQII PANYDDYVRA KADVKAKQAE VQQKRQNLEL IRSGEASIGQ
AKLSSTLYAP ISGTILNIKV EVGEPIISTE SSQAATEMIQ LADMKNIVFK GSVSEHDAAQ
LNAGMPASIT VAPYPEQVIN GQLTKVAIQS ERLNNPENKD GKSFDNGFQV EIGQLDIPEN
MTLRSGFSAS AKITLQRAAD VITLPERALQ FEGETPMVLI ADGSAQGYTA HPVKLGLSDG
VQVEILEGVA EKDSIVDNSM LGGQHE
//
