ID C3LN00_VIBCM Unreviewed; 343 AA.
AC C3LN00;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Multidrug resistance protein {ECO:0000313|EMBL:ACP05926.1};
GN OrderedLocusNames=VCM66_1615 {ECO:0000313|EMBL:ACP05926.1};
OS Vibrio cholerae serotype O1 (strain M66-2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=579112 {ECO:0000313|EMBL:ACP05926.1, ECO:0000313|Proteomes:UP000001217};
RN [1] {ECO:0000313|EMBL:ACP05926.1, ECO:0000313|Proteomes:UP000001217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M66-2 {ECO:0000313|EMBL:ACP05926.1,
RC ECO:0000313|Proteomes:UP000001217};
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001233; ACP05926.1; -; Genomic_DNA.
DR RefSeq; WP_001044382.1; NC_012578.1.
DR AlphaFoldDB; C3LN00; -.
DR KEGG; vcm:VCM66_1615; -.
DR HOGENOM; CLU_018816_1_0_6; -.
DR Proteomes; UP000001217; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF20; LIPOPROTEIN-RELATED; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
FT DOMAIN 59..251
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 343 AA; 37739 MW; 54333C95EA37A60D CRC64;
MNKTLLAFSI CSTLLVGCGK ELPPVPEPDS RPAKLTTVSV GNNTFSRQFP ATTAAGDRAV
LAFRVPGQLQ TIDVLAGQEV KKGEVLARLN PDEYALLEQQ ASANFQLADV QFQRAQRLRQ
DKVVSEQDFD QAQANHNSAK ATWEQAKANL RYTQLIAPYD GTISLIPAEQ YEYVAAKQGV
MNIQTNQLLK VQFLLPDHLL NRFSRDGVEA HMVFDSFPNR QYPLQFQEID TEADSKTRSY
KVTMVMERPN DVGILPGMAG RVSLMAPSGS ATVIPTSALF AEQGGKYVWR VDDAGLVSKA
AVTLNEQRQV LTGLNDGDRI IISGVSGVTE GIKVREWVKE RGL
//
