ID   C3LUV2_VIBCM            Unreviewed;       385 AA.
AC   C3LUV2;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=Integrase {ECO:0000313|EMBL:ACP07257.1};
GN   OrderedLocusNames=VCM66_A0280 {ECO:0000313|EMBL:ACP07257.1};
OS   Vibrio cholerae serotype O1 (strain M66-2).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=579112 {ECO:0000313|EMBL:ACP07257.1, ECO:0000313|Proteomes:UP000001217};
RN   [1] {ECO:0000313|EMBL:ACP07257.1, ECO:0000313|Proteomes:UP000001217}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M66-2 {ECO:0000313|EMBL:ACP07257.1,
RC   ECO:0000313|Proteomes:UP000001217};
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
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DR   EMBL; CP001234; ACP07257.1; -; Genomic_DNA.
DR   AlphaFoldDB; C3LUV2; -.
DR   KEGG; vcm:VCM66_A0280; -.
DR   HOGENOM; CLU_027562_0_4_6; -.
DR   Proteomes; UP000001217; Chromosome II.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   CDD; cd00801; INT_P4_C; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR038488; Integrase_DNA-bd_sf.
DR   InterPro; IPR025166; Integrase_DNA_bind_dom.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR   PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR   Pfam; PF13356; Arm-DNA-bind_3; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT   DOMAIN          202..385
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   385 AA;  44114 MW;  3DCAC20C16EFB1C5 CRC64;
     MSMAITDAWL RATNGKPYSG KTEISHRFGL GVRVSPKGKI TWVYRANING KMQRIKLGEY
     PAMKLRDAIQ ARESRAELVE LGFDPRKSTR SANDDSIITL NDLIDYWAEN HARDNIKQCD
     ALLKMFHTDI TPTLGNYPAK QLELIDFMPV FLKAKRRVSA KHSANLMTRF KQVLSYAVRH
     GLLKYNVLTE LKKADVGVPT TPKRSRQDEQ GVKALWKAID DISIHESNKN FLRLMLIFAN
     RSNELRLAKK ADFDLEKRVW TVPEENNKVR KKQGGAIRRA IPPLAEKIIM EQFAIWPNHT
     MMFPPVNTEQ DRPMSANVPV DFGSKLADRI EELGFPRTTN HDMRRTARNI WESMGVPYHV
     AETMLGHKVH TGVQSHYLGK MRLSL
//