ID C3LVH3_VIBCM Unreviewed; 469 AA.
AC C3LVH3;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN OrderedLocusNames=VCM66_A0516 {ECO:0000313|EMBL:ACP07478.1};
OS Vibrio cholerae serotype O1 (strain M66-2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=579112 {ECO:0000313|EMBL:ACP07478.1, ECO:0000313|Proteomes:UP000001217};
RN [1] {ECO:0000313|EMBL:ACP07478.1, ECO:0000313|Proteomes:UP000001217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M66-2 {ECO:0000313|EMBL:ACP07478.1,
RC ECO:0000313|Proteomes:UP000001217};
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
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DR EMBL; CP001234; ACP07478.1; -; Genomic_DNA.
DR AlphaFoldDB; C3LVH3; -.
DR KEGG; vcm:VCM66_A0516; -.
DR HOGENOM; CLU_055825_0_0_6; -.
DR Proteomes; UP000001217; Chromosome II.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd13706; PBP2_HisK_like_1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF5; BIFUNCTIONAL PERIPLASMIC SUBSTRATE BINDING PROTEIN_CYTOPLASMIC DIGUANYLATE CYCLASE; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 336..468
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 469 AA; 53284 MW; D31FF8DF868FD007 CRC64;
MTYKGYERMD HRFSTKLFLL LMIAWPLLFG SMSEAVERQT LTIANSKAWK PYSYLDEQGQ
PSGILIDFWL AFGEANHVDI EFQLMDWNDS LEAVKLGKSD VQAGLIRSAS RLAYLDFAEP
LLTIDTQLYV HRTLLGDKLD TLLSGAINVS LGVVKGGFEQ EFMQREYPQL KLIEYANNEL
MMSAAKRREL DGFVADTQVA NFYIVVSNGA KDFTPVKFLY SEELRPAVAK GNRDLLEQVE
QGFAQLSSNE KNRILSRWVH IETIYPRYLM PILASGLLLS IVIYTLQLRR TVRLRTQQLE
EANQKLSYLA KTDSLTDIAN RRSFFEHLEA EQTRSGSLTL MVFDIDDFKT INDRFGHGAG
DNAICFVVGC VRQALASDTY FARIGGEEFA IVARGKNAEE SQQLAERICQ RVAEKKWVVN
AQHSLSLTIS LGCAFYLHPA RPFSLHDADS LMYEGKRNGK NQVVFRTWS
//
