ID C3QMH3_9BACE Unreviewed; 366 AA.
AC C3QMH3;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EEO53157.1};
GN ORFNames=BSCG_00082 {ECO:0000313|EMBL:EEO53157.1};
OS Bacteroides sp. 2_2_4.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=469590 {ECO:0000313|EMBL:EEO53157.1};
RN [1] {ECO:0000313|EMBL:EEO53157.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_2_4 {ECO:0000313|EMBL:EEO53157.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., Lander E.,
RA Nusbaum C., Ilzarbe M., Galagan J., Birren B.;
RT "The Genome Sequence of Bacteroides sp. strain 2_2_4.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; EQ973355; EEO53157.1; -; Genomic_DNA.
DR RefSeq; WP_004296205.1; NZ_EQ973355.1.
DR AlphaFoldDB; C3QMH3; -.
DR GeneID; 29455365; -.
DR HOGENOM; CLU_018816_14_1_10; -.
DR Proteomes; UP000003969; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.20.50.140; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..260
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 100..165
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 366 AA; 40438 MW; 6960FFAC1050A417 CRC64;
MKKYLKITLL VVIAIILVGT FVFLYQKSKP KVITYETVRP EMTDLQKTTV ATGKVEPRDE
ILIKPQISGI IDEVYKEAGQ AVRKGEVIAK VKVIPELGQL NSAESRVRLA EINATQAETD
FARVKKLYDG QLISREEYEK SEVALKQARE ERQTAKDNLE IVKEGITKNS ASFSSTMIRS
TIDGLILDVP VKAGNSVIMS NTFNDGTTIA TVANMNDMIF RGNIDETEVG RIHEQMPIKL
TIGALQNLTF NAILEYISPK GVETNGANQF EIKAAITIPD SVQIRSGYSA NAEIVLQKAN
QVLAVPESTV EFSGDSTFVY IMTDSVPEQK FQRTQVTAGM SDGIKIEIKK GVTVQDKIRG
AEKKDK
//
