ID C3T0H7_ECOLX Unreviewed; 659 AA.
AC C3T0H7;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Formate-dependent uric acid utilization protein AegA {ECO:0000313|EMBL:EFF8956255.1};
DE SubName: Full=Oxidoreductase FeS-binding subunit {ECO:0000313|EMBL:QCL47104.1};
DE SubName: Full=Putative oxidoreductase Fe-S subunit {ECO:0000313|EMBL:ACI80211.1};
GN Name=aegA {ECO:0000313|EMBL:EFF8956255.1};
GN ORFNames=BTB68_004296 {ECO:0000313|EMBL:EFF8956255.1}, C9E67_07800
GN {ECO:0000313|EMBL:QCL47104.1}, ECs3330 {ECO:0000313|EMBL:ACI80211.1},
GN F9461_11885 {ECO:0000313|EMBL:EFH3673907.1};
OS Escherichia coli.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:ACI80211.1};
RN [1] {ECO:0000313|EMBL:ACI80211.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=493/89 {ECO:0000313|EMBL:ACI80211.1}, 86-24
RC {ECO:0000313|EMBL:ACI80212.1}, 87-14 {ECO:0000313|EMBL:ACI80213.1},
RC TB182A {ECO:0000313|EMBL:ACI80214.1}, and TW14359
RC {ECO:0000313|EMBL:ACI80215.1};
RX PubMed=19439656; DOI=10.1073/pnas.0812949106;
RA Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J.,
RA Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E.,
RA Sawyer S.A., Whittam T.S., Tarr P.I.;
RT "A precise reconstruction of the emergence and constrained radiations of
RT Escherichia coli O157 portrayed by backbone concatenomic analysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009).
RN [2] {ECO:0000313|EMBL:QCL47104.1, ECO:0000313|Proteomes:UP000298553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=143 {ECO:0000313|EMBL:QCL47104.1,
RC ECO:0000313|Proteomes:UP000298553};
RA Bono J.L., Arthur T.M.;
RT "WGA of Escherichia coli O157:H7: comparison of multiple isolates.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EFH3673907.1, ECO:0000313|Proteomes:UP000534496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CVM N19EC0189 {ECO:0000313|EMBL:EFH3673907.1,
RC ECO:0000313|Proteomes:UP000534496};
RG NARMS: The National Antimicrobial Resistance Monitoring System;
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:EFF8956255.1, ECO:0000313|Proteomes:UP000524010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PNUSAE005278 {ECO:0000313|EMBL:EFF8956255.1,
RC ECO:0000313|Proteomes:UP000524010};
RG PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; EU897660; ACI80211.1; -; Genomic_DNA.
DR EMBL; EU897661; ACI80212.1; -; Genomic_DNA.
DR EMBL; EU897662; ACI80213.1; -; Genomic_DNA.
DR EMBL; EU897663; ACI80214.1; -; Genomic_DNA.
DR EMBL; EU897664; ACI80215.1; -; Genomic_DNA.
DR EMBL; AASRHK010000063; EFF8956255.1; -; Genomic_DNA.
DR EMBL; AASVQO010000007; EFH3673907.1; -; Genomic_DNA.
DR EMBL; CP028607; QCL47104.1; -; Genomic_DNA.
DR RefSeq; WP_001078836.1; NZ_WTMA01000008.1.
DR PATRIC; fig|562.7073.peg.1570; -.
DR OMA; QRYATDW; -.
DR Proteomes; UP000298553; Chromosome.
DR Proteomes; UP000524010; Unassembled WGS sequence.
DR Proteomes; UP000534496; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd10554; HycB_like; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006006; GltD-like.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01318; gltD_gamma_fam; 1.
DR PANTHER; PTHR42783; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR42783:SF1; OXIDOREDUCTASE AEGA-RELATED; 1.
DR Pfam; PF13247; Fer4_11; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 78..107
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 659 AA; 71827 MW; 5FD819981777DC84 CRC64;
MNRFIMANSQ QCLGCHACEI ACVMAHNDEQ HVLSQHHFHP RITVIKHQQQ RSAVTCHHCE
DAPCARSCPN GAISHVDDSI QVNQQKCIGC KSCVVACPFG TMQIVLTPVA AGKVKATAHK
CDLCAGRENG PACVENCPAD ALQLVTDAAL SGMAKSRRLR TARQEHQPWH ASTAAQEMPV
MSKVEQMQAT PARGEPDKLA IEARKTGFDE IYLPFRADQA QREASRCLKC GEHSVCEWTC
PLHNHIPQWI ELVKAGNIDA AVELSHLTNT LPEITGRVCP QDRLCEGACT IRDEHGAVTI
GNIERYISDQ ALAKGWRPDL SHVTKVDKRV AIIGAGPAGL ACADVLIRNG VAVTVYDRHP
EIGGLLTFGI PSFKLDKSLL ARRREIFSAM GIHFELNCEV GKDVSLDSLL EQYDAVFVGV
GTYRSMKAGL PNEDAPGVYD ALPFLIANTK QVMGLEELPE EPFINTAGLN VVVLGGGDTA
MDCVRTALRH GASNVTCAYR RDEANMPGSK KEVKNAREEG ANFEFNVQPV ALELNEQGHV
CGIRFLRTRL GEPDAQGRRR PVPVEGSEFV MPADAVIMAF GFNPHGMPWL ESHGVTVDKW
GRIIADVESQ YRYQTTNPKI FAGGDAVRGA DLVVTAMAEG RHAAQGIIDW LGVKSVKSH
//
