ID C3XPW6_BRAFL Unreviewed; 931 AA.
AC C3XPW6;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=BRAFLDRAFT_118464 {ECO:0000313|EMBL:EEN69987.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739 {ECO:0000313|EMBL:EEN69987.1};
RN [1] {ECO:0000313|EMBL:EEN69987.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN69987.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN69987.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666451; EEN69987.1; -; Genomic_DNA.
DR RefSeq; XP_002613978.1; XM_002613932.1.
DR AlphaFoldDB; C3XPW6; -.
DR STRING; 7739.C3XPW6; -.
DR eggNOG; ENOG502QQI1; Eukaryota.
DR InParanoid; C3XPW6; -.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0017124; F:SH3 domain binding; IBA:GO_Central.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR030113; AFAP.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR14338; ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER; 1.
DR PANTHER; PTHR14338:SF7; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00169; PH; 2.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
FT DOMAIN 249..343
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 438..538
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 66..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..175
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 931 AA; 103027 MW; C3A83E13513E8D94 CRC64;
MDKLQALEEL LPGIQEYLCH QLSGEKLSRS AANQRLEFVK LLDKYKADTK TVPSIEAQED
EMYEDTLVPD KPPSSFLHQN GSGPSLVEDV NGDEYYEDTL PSSTNGSARP DSFIERQKIP
LPPIPGQGGE QDEEEYECPM AAPAQDGPPL PPRFPPTPAP TVALPPRPAA PLPTPQTEQA
PEAISEDTYE VPDVDPPAMG RMSVMSTPGG DSGDESGSYE DYDDDEEDTK KKEKRKKKES
KPEVFELPDA QISGVLQNKR LIGGWVKRFC AVKDSRFLAY KRATDEKPYV DMYLPGSSVV
YSEKEGKKQH VVKLVGGGDT HVLSVGNKAE ADRWIKLLEE ETQSGSGGML APGRAKVGRT
PSNVSDISRG SNSSRENEDV QDGNDSGKGG TLERQEDKRK SFGKDKKKKK KNKAGDFIVN
TFGKSKGKKL STQLSDSDIV IMGYLNISTT LLGDSKWTRR WCMIKNHYLE VHKNAKEDFA
ELTFPLKGCS LKPYTDETKK GKKDMAIQLN KHDVEIILEA ETSEDLGMWL RLLVEETGSS
NPDELSSLSC VYVDIEPDSK PDRPPMLKKV SQDSIISSGE AYMDLSYPDS NDQPAKLADK
SPKPSPKPSP KQPRKNEKAA TLEREKVKDG KKQDSVESED GKPKKEWKLT LGKQKKEKTS
DKSEKEEKEK KGGFMDRFKR KKNKSSEEKV EDKVEERDKE DARKPKGEKE EVKTVEKDVD
KKASTAGKST TEKEVEKKPS TTATAAPRYG KERAQAEVTR LENRKAELQA EKEKQRNKRV
ELRAKKQALK EKFITDQKLE EEIKGVSETL VDLEKELKET EAKLSKALKD SNPSPVLGRK
ASINTQDSPK LGKTSNSPAT TYKSSATVSL GKTDVKKQGT SSSPSVGKRI SKGVDDPVNS
AAKASGRPSS PKAGKKAVLE RAKQWEAMGG N
//
