ID C3Y2C6_BRAFL Unreviewed; 689 AA.
AC C3Y2C6;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=MIF4G domain-containing protein {ECO:0000259|SMART:SM00543};
GN ORFNames=BRAFLDRAFT_131114 {ECO:0000313|EMBL:EEN66016.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN66016.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN66016.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN66016.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NCBP1 family.
CC {ECO:0000256|ARBA:ARBA00007413}.
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DR EMBL; GG666480; EEN66016.1; -; Genomic_DNA.
DR RefSeq; XP_002610006.1; XM_002609960.1.
DR AlphaFoldDB; C3Y2C6; -.
DR STRING; 7739.C3Y2C6; -.
DR eggNOG; KOG1104; Eukaryota.
DR InParanoid; C3Y2C6; -.
DR GO; GO:0005845; C:mRNA cap binding complex; IBA:GO_Central.
DR GO; GO:0005846; C:nuclear cap binding complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0000339; F:RNA cap binding; IBA:GO_Central.
DR GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR GO; GO:0006406; P:mRNA export from nucleus; IBA:GO_Central.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IBA:GO_Central.
DR GO; GO:0050684; P:regulation of mRNA processing; IBA:GO_Central.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027159; CBP80.
DR InterPro; IPR015172; MIF4G-like_typ-1.
DR InterPro; IPR015174; MIF4G-like_typ-2.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF09088; MIF4G_like; 1.
DR Pfam; PF09090; MIF4G_like_2; 2.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW mRNA capping {ECO:0000256|ARBA:ARBA00023042};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 29..241
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 469..496
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 689 AA; 80629 MW; 0812E571002FA783 CRC64;
MSRRRRYSDD EDEGRGAKRR RTSEPLEIED RLESLITRVG EKSTSSLESN LEGLASVLEA
DLPNYKAKIL KILVDCAVQL PEKLSVYTTL VGLLNARNYN FGGEFVDAMV KRFKDSLKEN
KFEEGRVIVN FLADLVNCHV IAAPSLLAWY EAFVNVTLED DIPQVRADWF VYATLSTLPW
VARELYEKKE AEMERLLTNI DAYISKRQKV HVSILRVWSS DIPHPQEEYL DCLWAQIKKM
RMDKWQERQI VRPYLAFDNI LCEALQHNLP PYNAPPHTDD SSYPMPSVVF RMFDYTDAPE
GPVMPGHHSV DRYLIEENLR RIIDTYAVDR KECAAQLLNY PFKNKIPLNY HIVEVVYGQL
FQLPFAPHVD VFYTTLLIEL CKLQPSSLPQ VLAQATEMLY ERIDTMNIAC VDRFVNWFSH
HLSNFQFRWS WDDWTPCVEL DSSLYKPKFV QEVLGKCVSG SEDEMQDMDG VDEEEIERLQ
ERLESAQSEQ KKLFLVIFQR FIMVLTEHLG RCETSGKDFN TAWYRYSSER LQQIFLQHHS
TVTKYLDTLE NLLFTSDTDA HILRVFQQFC ALRAGSEDEM QDMDGVDEEE IEHLQERLES
AQSEQKKLFL VIFQRFIMVL TEHLGRCETS GKDFNTAWYR YSSERLQQIF LQHHSTVTKY
LDTLENLLFT SDTDAHILRV FQQFCALRA
//
