ID C3Y5K8_BRAFL Unreviewed; 665 AA.
AC C3Y5K8;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=BRAFLDRAFT_125060 {ECO:0000313|EMBL:EEN64255.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN64255.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN64255.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN64255.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666487; EEN64255.1; -; Genomic_DNA.
DR RefSeq; XP_002608245.1; XM_002608199.1.
DR AlphaFoldDB; C3Y5K8; -.
DR STRING; 7739.C3Y5K8; -.
DR eggNOG; KOG4773; Eukaryota.
DR InParanoid; C3Y5K8; -.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000931; C:gamma-tubulin ring complex; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IBA:GO_Central.
DR GO; GO:0033566; P:gamma-tubulin complex localization; IEA:InterPro.
DR GO; GO:0042554; P:superoxide anion generation; IBA:GO_Central.
DR CDD; cd12024; SH3_NoxO1_2; 1.
DR CDD; cd11856; SH3_p47phox_like; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR022214; MZT1.
DR InterPro; IPR035758; NoxO1_SH3_2.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15706:SF23; -; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF12554; MOZART1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 236..296
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 328..387
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 296..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 73328 MW; 881D66BDADA46468 CRC64;
MAEARTNSVR EAMDTLQEIS RLLNTGLDSE TLSICVRLIE QGVNPEALAS VIKELRRETA
ALKHVSLSPK NMGRLQVQAD MGGSSWSLRS DVSDSGRRLV DVQVVGVEKR YSPRRHHKQL
KEMFPVEAGQ FRVEERVLPK FPNKPSSPGL GRKFSVGRFA CVQKDLQGYC QDLLRLDSKI
VLSPLFQGFF APSDDDLRSS QNSEKRQKTV MIIPTEAAEP EQPRSPCDVE ISAPLFDLDS
YRAVADYKAV SKGELSLTAG EVCDVIHTTL SGWWLVENAS CERGWVPASH LEADTHTTTP
KLGTQSVGSP ATQPDHEAGS MSESGGEAPI QLYVTTRPYT ATEDDELSFC AGAVLQVLQR
TDDGWWLARY SGQDGFVPAM FLRPYNTPYV HMVAATSKLS MVNLLTAEKQ QRSNNNSRKG
SCSDVSRMSL LGEELSPGKG RAGSDISSIG LTDEGVSEVK NSIERDTNRK GDNFERADIL
SKREFQPSSK FDLPKITISI ADSAADCQAH SDTRQDTPNS PRIPPRPSEQ EIIQRCSPLT
QRRLLSTPST ATSDDDYTSV EGEALGAVWT GRQRKDSGLG IVNLSFEPCD YDHNEVCLDR
GDNTFSSITS VQSAFSFSKS TCWLDQEKTQ GEPSPNTVAA TSNGREEGAK FVRNNRLWMT
LKLKR
//
