ID C3Y5M1_BRAFL Unreviewed; 272 AA.
AC C3Y5M1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE RecName: Full=Nitric oxide synthase-interacting protein {ECO:0000256|ARBA:ARBA00016935};
DE AltName: Full=E3 ubiquitin-protein ligase NOSIP {ECO:0000256|ARBA:ARBA00029661};
DE AltName: Full=RING-type E3 ubiquitin transferase NOSIP {ECO:0000256|ARBA:ARBA00032934};
GN ORFNames=BRAFLDRAFT_59837 {ECO:0000313|EMBL:EEN64268.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN64268.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN64268.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN64268.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR023577}.
CC -!- SIMILARITY: Belongs to the NOSIP family.
CC {ECO:0000256|ARBA:ARBA00008126, ECO:0000256|PIRNR:PIRNR023577}.
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DR EMBL; GG666487; EEN64268.1; -; Genomic_DNA.
DR RefSeq; XP_002608258.1; XM_002608212.1.
DR AlphaFoldDB; C3Y5M1; -.
DR STRING; 7739.C3Y5M1; -.
DR eggNOG; KOG3039; Eukaryota.
DR InParanoid; C3Y5M1; -.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR CDD; cd16661; RING-Ubox1_NOSIP; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR016818; NOSIP.
DR InterPro; IPR031790; Znf-NOSIP.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13063; ENOS INTERACTING PROTEIN; 1.
DR PANTHER; PTHR13063:SF10; NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN; 1.
DR Pfam; PF15906; zf-NOSIP; 1.
DR PIRSF; PIRSF023577; ENOS_interacting; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR023577}.
FT DOMAIN 4..78
FT /note="Nitric oxide synthase-interacting protein zinc-
FT finger"
FT /evidence="ECO:0000259|Pfam:PF15906"
FT REGION 126..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 272 AA; 30231 MW; 4118F9802E69C7BF CRC64;
MTRHARNCTA GAVYTYHEKK KDTQQSGYGS QRARLSKDSI KDFDCCCLTL QPCKNPVVTP
DGYIYDKEAI LEYILHQKRE IARQLKAFDK QTKKLKEDEA QKQKSEKHSK IKAFVDKEKS
IVSKPLNPFI GAGPSKTKEQ TEPAGASAAG PSTSTGATGK DKQLPSFWIP SLTPKAEETK
LKKPEEKVRC PMSGRPLKMK DLIPVVFKPV NDRDNKTSLI VKQRLIKKDM TDPVSGDKLK
DRDIIPIQRG GTGFASSGVK LEAKQDGPVM QA
//
