ID   C3Y983_BRAFL            Unreviewed;       642 AA.
AC   C3Y983;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BRAFLDRAFT_118666 {ECO:0000313|EMBL:EEN63139.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN63139.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN63139.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN63139.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666492; EEN63139.1; -; Genomic_DNA.
DR   RefSeq; XP_002607129.1; XM_002607083.1.
DR   AlphaFoldDB; C3Y983; -.
DR   STRING; 7739.C3Y983; -.
DR   eggNOG; ENOG502QPS2; Eukaryota.
DR   InParanoid; C3Y983; -.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10338:SF157; -; 1.
DR   PANTHER; PTHR10338; INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER; 1.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..642
FT                   /note="VWFA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002935341"
FT   DOMAIN          54..184
FT                   /note="VIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51468"
FT   DOMAIN          328..473
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   642 AA;  71335 MW;  DDDC388EB8465398 CRC64;
     MVSLKAGWAL AAALCIFLVL AECESEGLHR KRDGEIAGFN VVIAGRLGSR DKVTERRVRR
     QDDVSDTVDV YWLHVDSRVT SRFATVTVES KLANRRDRGR EAVFTMQLPE TAFISNFSMV
     ISNTLYVGTV MKKGAAREAY DAAVEAGESA GHVAQESPRG REEFRISINV GAEEKVTFQL
     TYQEFLVRRL GIYEHVISIR PEQIIPDMRI SVDLRESQGF SFLRVPDIRT SDLLTDQSTD
     ELSSATVSRA SPEHYTVTYS PSEQEQAAMS TQGIMGDFVV QYDVIRQQQI GFIQVYGDYF
     VHYFAPTGLP VMPKNVIFVI DLREMDFFNI VTFSSRTKRW KSELQVANQE NIRAADTYVT
     SMAAHGGTNI NDAILEASVL LDPELRSRHD SHASMIVLLT DGQPTGGVTN TNHIIANARD
     SLAGNHALFC LGFGYDVSFE FLERLALQNG GFARRIYPDD DGELQLTSFF DEVADVTQTA
     FSNYFNGSEV VVAGRFPGAP PSNLHVTVTG NGAQDALSLV EDFQLASLAA PEGFVERLWA
     YLTIKDLLKK ERTATEEEQQ NKLKERALNM SLEYNFVTPL TSMVVLQNKR RGRPTNKMFD
     DLVQSFGSPG SGFGSYGSGA TSCRPWPFWV VASAIVYALL PP
//