ID C3Y9M2_BRAFL Unreviewed; 2643 AA.
AC C3Y9M2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=MAM domain-containing protein {ECO:0000259|PROSITE:PS50060};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_125174 {ECO:0000313|EMBL:EEN63278.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN63278.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN63278.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN63278.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666492; EEN63278.1; -; Genomic_DNA.
DR RefSeq; XP_002607268.1; XM_002607222.1.
DR eggNOG; KOG1216; Eukaryota.
DR InParanoid; C3Y9M2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008773; F:[protein-PII] uridylyltransferase activity; IEA:InterPro.
DR CDD; cd06263; MAM; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR005105; GlnD_Uridyltrans_N.
DR InterPro; IPR000998; MAM_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR19959; KINESIN LIGHT CHAIN; 1.
DR PANTHER; PTHR19959:SF118; LIPASE_3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03445; DUF294; 1.
DR Pfam; PF00629; MAM; 5.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 1.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00137; MAM; 5.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50060; MAM_2; 5.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..2643
FT /note="MAM domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002933422"
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..281
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 277..395
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 395..554
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 559..718
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REPEAT 1931..1964
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 2147..2306
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REGION 575..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 862..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2313..2610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1455..1482
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 585..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..1017
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 2643
FT /evidence="ECO:0000313|EMBL:EEN63278.1"
SQ SEQUENCE 2643 AA; 288571 MW; 53B9F2E37A9A8779 CRC64;
MACFNHLLTV FGTLLALAVT TWGEDSFADP SIMRPAGLDS VGLNVVVGVS ACVGLFVIGV
MAAIFYHLVT KSRSTTEVDR EQGPLGLKRT EFNVVVGSAA VIGVVLLAVI VVTCRSVYVK
NKNGGDRNVN CVMLGLVFAH LWTLSMQQVD SDVDLDFAQP LNKSILGYYM YIETSRQERD
DVARLISPTL PNNIRCLEFW YHMYGDHTEE LKVYTKPTGS SLPGDPIWSK TGDKGDVWQR
ARVHLEVSSD FKVVFEGVRG TSYRGDIAID DVSFGTTPCG GSYMYIETSG QQPRDVARLI
SPVLSTDSKC LEFWYHMYGE STEELRVYQS STGSSQLGTP IWSLTGDQGD VWYNATVDLA
AGSNLYLVFE GVRGSSFQGD IAIDDISVRT TSCGGDCNFD DRDVCGYQQD DTDDFDWSRK
YGSSGTTGTG PSSDHTGNGY YMYIETSSPR TQGDVARLMT PALPTNTKCL EFWYHMYGST
IGRLNIYQAP TGSSQLGPPI WSLAGEQGDA WNRARLNIVA NKNFHIVFEG IRGSGITGDI
AIDDVSFRST PCPDPPEDEN CDFDSSLCGY QQDNTDDFDW RRQRGSTLTD NTGPSSDHTS
GSGYYMYIET SSPQQPGDVA RLTSPSLSTD TRCLEFWYHM YGDSTEELRV YIRSTGSADL
GTPIWTETGD QGDVWLQATV DLVADRNFYV VFEGVRGTSF RGDIAIDDIS FRRTSCVEVT
TTTPLQTTTY EPSTEATTAS FEPSTTYMTT TKPATASPSV TTDIVTTDTV TTAATTLLQT
TTFELSTEGT TTTLEPSTTY LETSTAITTQ ETTQEATTAA ATTLEYTTTR PTTSTTITTS
TQQVFMTTEP ITAPVVTTDV TTLERTTESE TTSAVPTTIA TTQQPSSPEP TSTLEETTED
LSTHSPTTVD TTTEITTDEA TTHVTTTASP IVISSVSTTT ISQSTVAKET TTASHSPSTA
STDVDVPTTQ PPDTTSLSTT KQPQIHTTKQ STNKPEASTA TRSTPRPGPT KPSTGKPTTG
KAPPCGKDCT TVPDYKVTGK SEAQGGLSIG IIVGAGAGGA VVVILVVVII IVAVKCRRRG
KTDDDFYTFK MTSLADKLQD LELCLKSRHG QSHVVGYGRA LRKAILQMDL FLEAEIFKSL
GDLHLKEGML SKDSAELDKV AAMYTAALLR CNDSDIRQTL EHRIGYMEKL SRQLLQGYTP
QYQSLDSWSI TDINVLRVAE TCEKLDRSTS ICQPPAWQSV DVETVYTEAL VTAVENRDVF
LEIEILKSLG DLYIKKGREI CGVSEFSKAA TMYGRALTIC RDPGVKQTLH HRVLYTVKIW
GAIRMLVKRA RNGHCCRRGK YKGHLKKGKS SLAKADLISA EHHFAAALKT VHISDPTAEQ
CQREVEPLCK LGDVYSKRGQ QTGDGGDFVK AAALYNAAIV RSKNQVLIGN IVKAIEEVEK
SFLKSILRIH SNVSHKNTNR HKKQLKEMRD QIKLEMETID QQLDPYVHDE DDPCVKDIEA
RRAQAVRQLF ERIARERKGF ISQLVEECIG LMGPPPCKYA LIGLGSQATG LVTPYSDLEF
AILLEDESER CVVYFRNLTH YLHLKVVNLG ETILPSVGIE TLNNFHSGNP VDNWFYDSIT
PRGFAFDGSM PKASKTPLGR QETMNKPSSE LICTPKNMVS KLLKDVTLYL KEGYHLATIL
RNPCLIAGDQ KLISTYMAIT RKILQADRGK IAQQLAQETL RENYKSCNFK ETITAKMIDV
KKTLYRFPAV AVDYLSLSVH IVPTTVWETI EEMKNKQAIS DSNAHHLTVL ASISAELRLK
TYIANGGQKE KLSAMASMET MQNSQESYLQ TNNHDVQTNA LKLVFYLPNE KQLLRYYHTA
VPLKRVLSAI KQSGVEWSGM KKVSNSFPEF YDSSPKVQAE MYFKLCKYRQ AISYLNEALN
TSEGTETEEV VGLLNSIGHA SLFVGDHDKA ISFLEQALKM HEKITEKSTV PSTPTSHTLG
SILSNLGLAW GKAGDHRKEI CYLEQTLQIE RNTSGQSEAN SVIAISLANL GSAWYFEGDF
RKAISYYEQA QQAVVKANDE SSPHIDISSL LGNLGEIWGD LGEHRKSVSY HEQALQMNRR
MYGQHTAHPD IALSLGRLGK AFYREGDYRK AISYNEQGLQ MYRAIYGDCD FDTSLCGYQQ
DNTDDFDWKR QQGTTATENT GPSSDHTTGS AGYYMYIETS SQATGNIARL ISPSLSNNIK
CLEFWYHMCG DSIEELGIYT RPTGSSLPKD LIWSQTGDKG DVWQRARVHL EESSDFKVVF
EGVRGFGVYG DIAIDDISFK TVPCGIAIHA TTAVPEQSSQ SGSTKLVPTA SKTSTTDITT
ATYNTAQEST TDGAKTSEAT TKPAPTSSEP LTTTHESTTE VATTSEATTQ KPAPTASEPL
TTTQNSTTEV ATASEATTKP APTASEPLTT TQDSTTEVGT TSEATTKPAP TSSEPLTTTH
ESTTEVATTS EATTKPAPTA SEPLTTTQNS TTEVATTSEA TTKPAPTASE PLTTTQDSTT
EVGTTSEATT KPAPTASEPL TTTQDSTTEV GTTSEATTKP APTASEPLTT TQDSTTEVGT
TSEATTKPAP TASEPLTTTQ NSTTEVGTTS EATTSVFAVT TVATNTQPPT TFETVMDTTT
QEI
//
