ID C3YGB7_BRAFL Unreviewed; 516 AA.
AC C3YGB7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123};
GN ORFNames=BRAFLDRAFT_126783 {ECO:0000313|EMBL:EEN60638.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN60638.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN60638.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN60638.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- FUNCTION: Phosphorylase b kinase catalyzes the phosphorylation of
CC serine in certain substrates, including troponin I. The alpha chain may
CC bind calmodulin. {ECO:0000256|ARBA:ARBA00002837}.
CC -!- PATHWAY: Glycan biosynthesis; glycogen metabolism.
CC {ECO:0000256|ARBA:ARBA00005131, ECO:0000256|RuleBase:RU364123}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364123};
CC Lipid-anchor {ECO:0000256|RuleBase:RU364123}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU364123}.
CC -!- SIMILARITY: Belongs to the phosphorylase b kinase regulatory chain
CC family. {ECO:0000256|ARBA:ARBA00007128, ECO:0000256|RuleBase:RU364123}.
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DR EMBL; GG666511; EEN60638.1; -; Genomic_DNA.
DR RefSeq; XP_002604627.1; XM_002604581.1.
DR AlphaFoldDB; C3YGB7; -.
DR STRING; 7739.C3YGB7; -.
DR eggNOG; KOG3635; Eukaryota.
DR InParanoid; C3YGB7; -.
DR UniPathway; UPA00163; -.
DR GO; GO:0005964; C:phosphorylase kinase complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011613; GH15-like.
DR InterPro; IPR008734; PHK_A/B_su.
DR PANTHER; PTHR10749; PHOSPHORYLASE B KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10749:SF7; PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED; 1.
DR Pfam; PF00723; Glyco_hydro_15; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860,
KW ECO:0000256|RuleBase:RU364123};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU364123};
KW Cell membrane {ECO:0000256|RuleBase:RU364123};
KW Glycogen metabolism {ECO:0000256|ARBA:ARBA00022600,
KW ECO:0000256|RuleBase:RU364123};
KW Lipoprotein {ECO:0000256|RuleBase:RU364123};
KW Membrane {ECO:0000256|RuleBase:RU364123};
KW Prenylation {ECO:0000256|RuleBase:RU364123}.
FT DOMAIN 8..491
FT /note="GH15-like"
FT /evidence="ECO:0000259|Pfam:PF00723"
SQ SEQUENCE 516 AA; 58175 MW; B3C75D65A3EAA4B9 CRC64;
MRSRSNSGVR LDYYQHLVHK TILIHQNPIT GLLPASIDQN HAWVRDNLYC IMAVWGLSLA
YRKTADMDED RAKAYELEQS VVKLMRGLLQ CMMRQVDKLE KFKYTQATTD ALHAKYNITT
CGTVVGDKEW GHLQIDATSL YILMLAQMTA SGLQIIFTLD EVAFIQNLVF YVESAYRTPD
YGMWERGDKT NHGWPELNAS SIGMAKASLE AIKEMDLFGS RGGPASIIHV MADEISQCKE
IDASLLSILS YPAFAVEDVD LSNLTKNEII SKLEGRYGLS RFLRDGYKTP MEDSGRLHYE
PWELSVFEGI ECEWPLFWTY LILDGLFKGD KAQVLEYKEK LAEVMVKGED GLPLIPELYI
VAPDKVDAER QNPGSQERSP GGKMPHMWSQ SLYILGCLIQ EGYLAPGEID PLNRRLIGQP
RPDLVVQVSI LAEDLYIQDL LKEHGIDVQT TQEVANIRCQ PARVLSHIYH HLGQNAKLGL
SGRPSYDIGL LGTSQLYTLK GQTFAFTPQV ENGVFV
//
