ID C3YGP5_BRAFL Unreviewed; 370 AA.
AC C3YGP5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 5 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_79389 {ECO:0000313|EMBL:EEN60555.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN60555.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN60555.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN60555.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
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DR EMBL; GG666512; EEN60555.1; -; Genomic_DNA.
DR RefSeq; XP_002604544.1; XM_002604498.1.
DR AlphaFoldDB; C3YGP5; -.
DR STRING; 7739.C3YGP5; -.
DR eggNOG; KOG1385; Eukaryota.
DR InParanoid; C3YGP5; -.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004382; F:GDP phosphatase activity; IBA:GO_Central.
DR GO; GO:0045134; F:UDP phosphatase activity; IBA:GO_Central.
DR GO; GO:0009134; P:nucleoside diphosphate catabolic process; IBA:GO_Central.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF83; NTPASE, ISOFORM F; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2}.
FT ACT_SITE 120
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 151..155
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 370 AA; 40971 MW; 612855369B95C3F1 CRC64;
MIDAGSTGSR LHVFKFRRNS EDDITLVSEK FESIKPGLSS YADDPDEGAA SIRGLVQIAQ
EVVPVAMQRT TPLALKATAG LRMLPEAKAQ TLLDKVQEVF EASPFLVRKD SVVVMNGLDE
GLFAWFTVNF LIGALGSKEK HSTKGALDLG GGSTQITFSP RDKETLRSSP ESFVRPVTIF
HKTYMLYVHS YLGFGLMAAR LRMMGMETED INRRSVKGSL RSACLPADFR GAFEHSGMEY
PVSGLPEGEA GFGACWAAAL AMVSRRIHQP DEVRQEPFYA FSYYFDRAKE SGMIGEEGGS
LKVSKFKQRA EEVCRKPLPE YPFMCMDLCY ISALLQEGFG FNPNNVLMLR KKIDGVETSW
ALGATFRMLS
//
