ID C3Z3I3_BRAFL Unreviewed; 512 AA.
AC C3Z3I3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_215938 {ECO:0000313|EMBL:EEN53027.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN53027.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN53027.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN53027.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG666576; EEN53027.1; -; Genomic_DNA.
DR RefSeq; XP_002597015.1; XM_002596969.1.
DR AlphaFoldDB; C3Z3I3; -.
DR STRING; 7739.C3Z3I3; -.
DR eggNOG; KOG1217; Eukaryota.
DR InParanoid; C3Z3I3; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 13.
DR Gene3D; 2.10.25.10; Laminin; 13.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 12.
DR Pfam; PF12661; hEGF; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 13.
DR SMART; SM00179; EGF_CA; 13.
DR SUPFAM; SSF57196; EGF/Laminin; 10.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 13.
DR PROSITE; PS00022; EGF_1; 15.
DR PROSITE; PS01186; EGF_2; 14.
DR PROSITE; PS50026; EGF_3; 14.
DR PROSITE; PS01187; EGF_CA; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..15
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 17..53
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 55..91
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 93..129
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 131..167
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 169..205
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 207..243
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 245..281
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 283..319
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 321..357
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 359..395
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 397..433
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 435..471
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 473..509
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 5..14
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 43..52
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 81..90
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 119..128
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 157..166
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 195..204
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 233..242
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 271..280
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 309..318
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 347..356
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 385..394
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 423..432
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 461..470
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 499..508
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEN53027.1"
SQ SEQUENCE 512 AA; 54777 MW; A36E1C6548B94F88 CRC64;
YMCICSRGWI GLTCEEDTNE CSSNPCNNNA TCRDEVNSYA CACADGWEGL HCDIDTDECS
SNPCKNNATC HDELNSYTCA CADGWEGLHC DIDTNECSSN PCKNGATCHD GLNNYTCKCL
AGWKGLHCDN DTNECSSNPC QNGATCHDGI NSYTCGCVAG WEGLHCDNDI DECFCNPCKN
GATCHDGLNS YTCECGAGWE GLHCENDTNE CSSDPCQNGA TCHDELNSYT CECVKGWEGL
HCDIDTNDCS SNPCNNNATC HDGLNSYTCA CVAGWEGAHC DIDTNECSSN PCQNGATCQD
EANSYTCECG DGWEGQHCDN DTNECSSDPC KNGATCHDEL NNYTCVCVAG WEGEHCDIET
DECSSSPCQN GATCHDGLNN YTCTCTDGWE GLHCGIDTDE CSSDPCQNGA TCHDELNSYT
CACVAGWEGT HCDIDTNECS SNPCQNGATC HDEANSYTCE CGDGWEGLHC DNDTNECTSN
PCQNGATCHD GLNNYTCTCV AGWEGAHCDI GK
//
