ID   C3Z4S3_BRAFL            Unreviewed;       680 AA.
AC   C3Z4S3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 51.
DE   RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
GN   ORFNames=BRAFLDRAFT_121587 {ECO:0000313|EMBL:EEN52445.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN52445.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN52445.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN52445.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666581; EEN52445.1; -; Genomic_DNA.
DR   RefSeq; XP_002596433.1; XM_002596387.1.
DR   AlphaFoldDB; C3Z4S3; -.
DR   STRING; 7739.C3Z4S3; -.
DR   eggNOG; ENOG502QTUW; Eukaryota.
DR   InParanoid; C3Z4S3; -.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   PANTHER; PTHR15603:SF4; DEATH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15603; SH3 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00531; Death; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          493..554
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          344..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   680 AA;  77219 MW;  D94D64329229C12A CRC64;
     MAANSSDRSG GEPPLSPREA NQPFSYAAAV RPKKRSAKNG QKKKKDDGPP CQPEVISSEV
     GSDGGVIETT CKDVVLYIPR NYSSENGVQN VTVTMATDYP PEAQGPQKAV VTPMVKVELS
     EPEKVKKNLV MDIEMNARIK EDEKKTTHIE CLQSSSSDSG FEAVDRRLYR MLPGSNIIRL
     LLQGPLQQNF IMVVAKTVKE YIWDTLERKV TFAVFGPCVL QTSMVPVLFY SSHGLRGLLA
     WYDSLKERMG SSSQAEGNVQ WGESYDFYMD KPQTLEVIAS LEKTSCWAVK DENKQKIISK
     EAVEKRWNGK HGFVVLKKSG KKTDPFALTF NIKPEEKSRP FVFHVATPAG PPDSAPTSPR
     LKRRRRGTPQ RKLSACQNAM APSVIICDVV KAKVTRRRSQ WYQLDYDKGQ LIPVLTNQGV
     FGHSEKVLKE YWVGYTDGRV GFFRRDDVEI VEGFRPEVCP TKDGLLRSLL EPCRHLKFNY
     NFIRQEMVNN LVKWPRFARQ VGFNEADIED IKVRHRDDSK EQVAAMMEDL RQRTGEGKPE
     LLMTVMEGLF RCGIPYKKID CPHLALKILL DSLLYTVALS THPNYMKLGA ELGYNIIHLM
     RINKQCKGAS RPEKACQPEY AILQEWQAQK WSGKRQDPVD MLQWLHIVVQ EMGGEGNPNQ
     EFRHIQGVIL FLLCYKRIPL
//