ID C3Z9X0_BRAFL Unreviewed; 2531 AA.
AC C3Z9X0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 06-MAR-2013, entry version 26.
DE SubName: Full=Putative uncharacterized protein;
GN ORFNames=BRAFLDRAFT_104468;
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae;
OC Branchiostoma.
OX NCBI_TaxID=7739;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82; TISSUE=Testes;
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J.,
RA Gibson-Brown J.J., Grigoriev I.V., Horton A.C., de Jong P.J.,
RA Jurka J., Kapitonov V.V., Kohara Y., Kuroki Y., Lindquist E.,
RA Lucas S., Osoegawa K., Pennacchio L.A., Salamov A.A., Satou Y.,
RA Sauka-Spengler T., Schmutz J., Shin-I T., Toyoda A.,
RA Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W., Satoh N.,
RA Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Contains 1 FAT domain.
CC -!- SIMILARITY: Contains 1 FATC domain.
CC -!- SIMILARITY: Contains 1 PI3K/PI4K domain.
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DR EMBL; GG666601; EEN50558.1; -; Genomic_DNA.
DR RefSeq; XP_002594547.1; XM_002594501.1.
DR GeneID; 7212623; -.
DR KEGG; bfo:BRAFLDRAFT_104468; -.
DR eggNOG; COG5032; -.
DR KO; K06640; -.
DR OMA; DHYSTGD; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR Gene3D; 1.10.1070.11; -; 1.
DR Gene3D; 1.25.10.10; -; 3.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011009; Kinase-like_dom.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR003151; PIK-rel_kinase_FAT.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR011990; TPR-like_helical.
DR InterPro; IPR012993; UME.
DR Pfam; PF02259; FAT; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF08064; UME; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SMART; SM00802; UME; 1.
DR SUPFAM; SSF48371; ARM-type_fold; 1.
DR SUPFAM; SSF56112; Kinase_like; 2.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW Reference proteome; Transferase.
SQ SEQUENCE 2531 AA; 285099 MW; 79958E35E7547382 CRC64;
MRMSQELSKT SGGMPQCQML LQFIRHGVDN FPWLFVHEPV SSDDPSPDTS QARGDLTLTQ
DGYRVSKEPK CEPLHSISLD ILTSLMHMIR IKDVFMYQEL ATEFLALIGS LISISKTVFR
FGEITTTDQP IRLEYFVQQD DTSASGSQTM KDEPISIKYF ANLYLLQIAL RDVAGLERSL
AGCLNAVFQV DEKTNSPVHC IPPHHVCATL EMLSVLLSAN GLDNLHTKEL RSCVCGLLCY
IYRHVPEGYE GCVSLRQHHL QQAVLGLLQH LGTAVHLGTA AGSQQYLVPC LFEAISAKMP
PIKGDDPARG QVSSDQESAS SGDEKLEKRA KLSRRRSLLP TQSQRATSSK QQKQTGESQS
TEKPEVYQLL EKKLQELCLK LQQEPTKETA LSLLEGIRVA VEVSVRCAAS RGIVKEWLPA
SYLQNLCSVW FNTLKQAPAL LSKNDLKECY LLVVQSIGAV LSVSDISAFG GENLRFMTMV
LSFPWLLEDQ NWLDLRVSGW CSAKEAADLC GQFAEAIGGE AESLCVHLLA LVPREVAPKW
RIHIMKAALN DSRVQVRTSL VRSFPILLHT LGHNSHHLVY DILQNNSSDD HLYKVTRLGC
SVCQQKGMVE SIPELFSHIR VSADVPASMS LLQNFLSPVE DSSYDVRMAF SKQVGHLARG
WLSDSSSPLV AKLKSAYLRA NSSSNSIPLQ ETVVLTIGQL GRIAEGDLFG VVLINLLISL
VSQSPVLAAL AYSEIHDIAK VRKTNLTSLL TKQRPIICKW LSEVLHDSQG SGGSSTCRLK
NPAGILSEVA SVFGCEDVRK FLLMCLQTLL PQLVHKACPE TSAIIRLIAK ELEMNRQDLL
INNFKYIFRY LACNCKTEEK ERALEFVQNE TQIELRSLLR SDYQGLHNEL LLYISSHYSQ
VFAGLATVAA STREGKGKGK VPREITTAQE MGYQGDHYST GDGGYIKGYQ GDHYSTGDGG
YIKGYQGDHY STGDGGYIKG YQGDHYSTGD GGYIKGYQGD HYSTGDGGYI KGYQGDHYST
GDGGYIRVTR EITTAQEMAE FLQPCLLGIL AFFDSQLLTT SIPMEDKKLA LESLITLMKL
MGPKHITAVR VKVMTTLRIC LRFKVKGFPE LSCRAWDCFV HSVELSCLGP MLSQIVVTLL
PLLQTQAKPV AGVFSFLIQD NREALQDHFH ELYFMPELPE LSKINAVLKQ HIETPSSQSD
LKSQLKHSLK GLGHESLDVR LHALSKLKQQ LHANQLLSSC RESDKTARSL VGECLGELGA
IDPGRLDLKA HGQKEELSKF QAGVDDINFA HDLIMELARA FLAATDTRSQ DCSAFSIQEI
LQTYECREGT KDTLGRRLWR GFPEHIQEIL LPHLHSKYIV FSTATWTNMK KPIYRSNKGS
TFQDWVYNWT GYLITKVKQD MASRVFRACS TVTKYNETTA LFLLPHVLLH ALLDGSTEEK
QEACNEILAV LKYAEKMEEK GAQDFSHMAA QTVFSVLDHL TRWCRHRQLT LSVQRDDGKK
GNRSSDRVLL RDDSPYNSVQ GFLDLIPQDV LAVASFHCRA YTRALMHFES YLSASKPDIE
PQLCLLQKLY VAMDEPDGVA GVMAIRKSEP DIKEQILQHE SIGELRDASA CYERALQTEA
STVPHHQGLL RCLLGLGQLT TAMVHVNGVL ADKPEWTKDL NAFRVEASWQ LGNWDGLENY
LKVYNGKSES KGSSNWSVGL GKILLAAKHR DEEDFWHQLQ IVRNDQMGPL SAASMESGSY
QRGYDYIVRL HMLCELQHGV KVLLRREDAG EQEDGSLDLE ARARITQSSF RTREPLYSLR
RCIINMAGSP DTVGKELGHC WLQSAKIARK AGHLQTAYSS LLNASTYSLP ELLVEKAKWL
WHQNDQHQAL ITLQKGVAEH FSDTAYMNCG SSEAANAKKH THAKALLLVG RLMEDTAMYD
SNQVMKQYKS VVEVYQEWED GHFYLAKYYD RIMTTMRETP VKAGEIILYV VTYFGRSLQY
GNQHIYQSMP RLLALWLDYG AKVSDLEKDV FEVRWHFFFS AGRAERSNMR VLLPKLNEII
ANLTRKLAPY QFLTSFSQLI SRICHSHAEV LTRLEDIIAM LLVTFPQQCM WLMMAVSKST
SLIRKKRCQD IFKKAKSMNS ELNQFIQDAT RLADKLLELC NKPVDPGVQH FSLSLHFKSL
KRLLEDRKFS PILMPLQSAL TVTLPSGPGP HANHEPFPAA LVYIAGFEDT VELLPSLQRP
KKFSFRGTDG HSYIMMCKPK VEVLSSAAKP KKIAVRGSDG KAYFLMCKPH DDLRKDCRLM
EFNAIVNKCL RKDPESRRRQ LYIRTYSVVP LNEECGLIEW VNNTHPLRQV LIKIYKERLH
MFQNTILPKH PPVFREWFLK VFPDPTSWYQ ARLNYCRTTA VMSMVGYILG LGDRHGENIL
FDSTNGDCVH VDFNCLFNKG ETFDWPELVP FRLNTTWSTQ CVLRSFIFDP LVEWSRVNKS
TRSVVPESGE ISNEKAMTHV RDIDQRLQGV FKKMRGLPLS IEGHVHHLIQ INGTFTLKAY
SRKPLELDYK G
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