ID   C3ZBM4_BRAFL            Unreviewed;       871 AA.
AC   C3ZBM4;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   RecName: Full=Roc domain-containing protein {ECO:0000259|PROSITE:PS51424};
DE   Flags: Fragment;
GN   ORFNames=BRAFLDRAFT_164586 {ECO:0000313|EMBL:EEN50261.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN50261.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN50261.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN50261.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666603; EEN50261.1; -; Genomic_DNA.
DR   RefSeq; XP_002594250.1; XM_002594204.1.
DR   AlphaFoldDB; C3ZBM4; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   InParanoid; C3ZBM4; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 3.30.70.1390; ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR032171; COR.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020859; ROC_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48051; -; 1.
DR   PANTHER; PTHR48051:SF39; MALIGNANT FIBROUS HISTIOCYTOMA-AMPLIFIED SEQUENCE 1 HOMOLOG; 1.
DR   Pfam; PF16095; COR; 1.
DR   Pfam; PF08477; Roc; 1.
DR   SMART; SM00364; LRR_BAC; 6.
DR   SMART; SM00369; LRR_TYP; 7.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS51424; ROC; 1.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          274..504
FT                   /note="Roc"
FT                   /evidence="ECO:0000259|PROSITE:PS51424"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEN50261.1"
FT   NON_TER         871
FT                   /evidence="ECO:0000313|EMBL:EEN50261.1"
SQ   SEQUENCE   871 AA;  99596 MW;  4C663D4BB20FC629 CRC64;
     TAAGNVKAVR LTDRSLSRIP DDVLEKEEVE HLFLSRNRLV VLPSNFTRLG CLTRLYLDNN
     CLSAFPSELF ALSELEELSL ADNNIDSLPE QISIFRKMET LLVFGNMLHS LPSSIGSLSL
     LKSFDVHRNH LKELPASFGQ LQNLKNLYLS QNQFEEVPPV VLDVGDSLQV LEVAMNKLRH
     LPEAIDRLKV IKRIDAGENK IASVPKTMCN LSKLEWLSVM DNCIQELPDT FGQLASSLKY
     LSTTNNPLVQ PPYEVCEQGI QAILKYQEEL QRCRAVVQPK MKMVLLGSPF AGKTSLCHAL
     MEERSRLTRE EDRTHCMDVK LWQADEDLQL EVYDFGGHKV YDFVHQFFLS PLAMNVLTVN
     LEQYKPAEFE ELVGKWAKAL NAHTPGAVVR LVGTHVDRCS PKDVRWKCED ICDQLHRDKK
     KQDQIIQDQM KTIEDVISDS SVIEVGHPLH GVTRERMLKR YHKLRAMLES QPKLQWCVAQ
     VSSADPLKGI EDLKKELVSL ALNKDVFPAL CRVLPETWVS LEQRMLAERK KPTLWLTMEE
     VETLGWEVGL SADRLHPAIA YLHKRGVVLY FNDIPDLKNV VFQNPARLTD ILKQLYHHNT
     DTMIRNISSL KVDHIQQRQL QEDLLRSGLM SIDTLHHLLK GMKQPPNNIG IVVQLLERFG
     ICYPVPMSGA GSIARAYRTE SSSLYQFTWL LSTEMPGDVH EKWFPVCPEK QDQLTILCVM
     RGFTPWGLYE RFCAQIDPHI GNRLDWANGI LASFGDFPLH VRREVNKENN ASITMATRFP
     MDHVDKAWED LLKVYGVLRS LLKEWPGLPY TFWIGCCHCL KKEDAARGQP HYFPGDLLRQ
     RRPLGIHSLR CRRCSASETV DIRLVYPPSV T
//