ID   C3ZBP2_BRAFL            Unreviewed;       530 AA.
AC   C3ZBP2;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 68.
DE   RecName: Full=Rhophilin-1 {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=BRAFLDRAFT_165175 {ECO:0000313|EMBL:EEN50279.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN50279.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN50279.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN50279.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666603; EEN50279.1; -; Genomic_DNA.
DR   RefSeq; XP_002594268.1; XM_002594222.1.
DR   AlphaFoldDB; C3ZBP2; -.
DR   STRING; 7739.C3ZBP2; -.
DR   eggNOG; KOG2220; Eukaryota.
DR   InParanoid; C3ZBP2; -.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IBA:GO_Central.
DR   CDD; cd09244; BRO1_Rhophilin; 1.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR047138; RHPN1_2.
DR   PANTHER; PTHR23031:SF15; LD12055P; 1.
DR   PANTHER; PTHR23031; RHOPHILIN; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM01041; BRO1; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51180; BRO1; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          50..439
FT                   /note="BRO1"
FT                   /evidence="ECO:0000259|PROSITE:PS51180"
FT   DOMAIN          453..530
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   COILED          16..43
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEN50279.1"
FT   NON_TER         530
FT                   /evidence="ECO:0000313|EMBL:EEN50279.1"
SQ   SEQUENCE   530 AA;  60047 MW;  FF57B5CEBD0FE514 CRC64;
     RACNSRKMKE TVALELSFVN SNLQLLKEEL SDLNSSVEVY QSDSESRATP MIPLGLKETK
     DVDFNVPFKD FILEHYSEDS SEYDGELKEL HDLRRAMRTP ERDEAGIELL MEYYNQLYYV
     EKRFFPPNRH LGIYFHWFDS LTGVPSSQRT VAFEKGSVLF NIGALYTQIG AKQDRTKKDG
     INAAIDAFQK AAGAFKYLQD NFSHAPSMDM GLETLEALIK LMLAQVQECV FERRVLDGWE
     ENLTNCLTVA QESAKVSEAY SMVHKAMNTP PVKDYVPFSW ISMVLVKSEH FKAQSHYLAA
     VGFIDQKGTS DNDEDELEKL LSQVHLRDAD SPSTLATDRE DRKQLGKAHL REALILHEDA
     LRVHRMCKKL RQIDTLGTIL KEAHNKSMTK YSDVEEEDEF YDEVIAPRIQ PKTHQRPEIK
     PPNFANVKVV DIFHRLGPLA VFSARNQWSV PRTCSMEKGE QGFGFVLRGD SPVIVAEVEP
     GSKAAQGGVK PGDFIVAVDG RNVKWGKHHE VINLILSCGE QVSMQVVTPQ
//