ID C3ZCJ4_BRAFL Unreviewed; 570 AA.
AC C3ZCJ4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=BRAFLDRAFT_107668 {ECO:0000313|EMBL:EEN49698.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN49698.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN49698.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN49698.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG666608; EEN49698.1; -; Genomic_DNA.
DR RefSeq; XP_002593687.1; XM_002593641.1.
DR AlphaFoldDB; C3ZCJ4; -.
DR STRING; 7739.C3ZCJ4; -.
DR eggNOG; KOG3717; Eukaryota.
DR InParanoid; C3ZCJ4; -.
DR GO; GO:0005777; C:peroxisome; IBA:GO_Central.
DR GO; GO:0004092; F:carnitine O-acetyltransferase activity; IBA:GO_Central.
DR GO; GO:0019254; P:carnitine metabolic process, CoA-linked; IBA:GO_Central.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF103; CARN_ACYLTRANSF DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 11..432
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT DOMAIN 434..555
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 314
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 570 AA; 64241 MW; ED44E011AFB62FB0 CRC64;
MVSHQSSLPC LPVPDLCQTL EKYLLTVRPL VDDTAFQKTK QLVEEFGKSG GLGESLQTKL
KKRAQERQNW LDDWWLHTAY LDYREPVVIH VSPGIVCPPQ NFSGKEEQLQ FAAKLVAGVL
DYKVQIDDQS VPIDKLRTQP LCMDQYYKLF SACRLPGDQR DQVVVYGPDC DDRPRHIVVV
HNNQFFSLDV YDNNWKPLSQ DLIHAQLQRV VCQSKDPGMP VGILTTENRD TWGRVYKALK
KDKHNKMSLE AINKSMFMLC LDQETDRGAD RWTSMGHQLM HGGGSQLNSG NRWFDKTLQF
IVGTDGAVGI VYEHSPAEGP PIIALLDHML DFCSQAPEVK GPSVQPMEPE RLFFSLNDSV
LEAIDNAKQN LDIQVQDLDL HLVMFKTYGK DFPKSQRLSP DSYIQMAMQL AFYKVYKVAS
ATYESGSTRM FHGQQSEKVA LLRRAVEGHK KYAQETVSGQ GIDRHLLGLK LIAVEAGLDV
PDLFVDSTYQ QAMHFKLSTS QVPSKYDSLL CFGPVVPDGY GVCYNPAQDH LNFCISAFNS
SLQTDTGKLA AALQQSLLEM QELLQTQAKL
//
