ID C3ZHU9_BRAFL Unreviewed; 305 AA.
AC C3ZHU9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=TIR domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_89399 {ECO:0000313|EMBL:EEN47893.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN47893.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN47893.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN47893.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG666624; EEN47893.1; -; Genomic_DNA.
DR RefSeq; XP_002591882.1; XM_002591836.1.
DR AlphaFoldDB; C3ZHU9; -.
DR STRING; 7739.C3ZHU9; -.
DR InParanoid; C3ZHU9; -.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR CDD; cd00045; DED; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR47508; SAM DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR47508:SF1; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00114; CARD; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF47986; DEATH domain; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50168; DED; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
FT DOMAIN 9..87
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
FT DOMAIN 98..173
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 163..282
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 305 AA; 34712 MW; 7EC202CAD0B0D174 CRC64;
MAGADERRTR QDLYLEISRE LTDEEVSDIR GYIGGKQLPT GSIQRATAQE MFNMLERKRI
LKKGDLSFLV KLMESIDRQE FAEAANEIAE QESEDKGSAE ELEALITRNR VLLTKRLQVS
SLFPHLIERG LLLIDEKEDI NSKTTTQGKA EALLDLLSRQ GKCTPDVFME ILKLGNHEHI
VIQLRDVLEK KGYSCWMDIT KMGGGDKLHA EIDRGIRQAK VVISCVTPNY TKSDSCQNEV
ELAYRLKKPL VPVLLEKTAW PPEGPMAMPF AQLLYIDFTK ESKEHPWKGA KLNDLITSLE
QRLKQ
//
