ID C3ZI46_BRAFL Unreviewed; 595 AA.
AC C3ZI46;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=BRAFLDRAFT_83552 {ECO:0000313|EMBL:EEN47788.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN47788.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN47788.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN47788.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; GG666626; EEN47788.1; -; Genomic_DNA.
DR RefSeq; XP_002591777.1; XM_002591731.1.
DR AlphaFoldDB; C3ZI46; -.
DR STRING; 7739.C3ZI46; -.
DR eggNOG; KOG3717; Eukaryota.
DR InParanoid; C3ZI46; -.
DR GO; GO:0005777; C:peroxisome; IBA:GO_Central.
DR GO; GO:0004092; F:carnitine O-acetyltransferase activity; IBA:GO_Central.
DR GO; GO:0019254; P:carnitine metabolic process, CoA-linked; IBA:GO_Central.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF103; CARN_ACYLTRANSF DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 11..580
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 314
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 595 AA; 66983 MW; FCEC8848F0C63E79 CRC64;
MLAHQANLPR LPVPALSQTL QKYLSAVRPL LDDDEFQHTT KLVEEFGKAG GLGESLQAKL
QMRALERQSW LADWWLHTAY LDFRMPVVMH VSPGVVCPPQ NFNGQEEQLK FAAKMVTGLL
DYKVQIDNQS VPIDKLGKNF LCMDQYYKLF SACRIPGERR DQVVVYGPGS NVRPRHIVVA
HNNKFFSLDV YDENWKPLSQ DLIHAQLQKV VYYSRYPSEP VGILTSENRN TWGKVYKLLK
KDKTNKASLD AINKAIFMLC LDQEVSRGED SKASMAHQLM HGGGSELNSG NRWFDKTLQF
TVGTDGAIGL TYEHSPAEGP PIISLLDHMM DYCSQAPDVK ETTVQPKEPE RLPFTVNDKI
LEAIDTAKRN LDVQVKDLDM KPVTFQEYGK GFPKSQKMSP DSYIQIALQL AYYKLYKVPC
ATYESGSTRM FHLGRTDTIR SASVESLEFC KAMEDSGIPP GEKVALLRRA IEGHKKYAQE
TVSGQGIDRH LLGLKLTAIE AGLNVPELFM DSAYEQALHF KLSTSQVPSK YDSFLCFGPV
VPDGYGFCYN PREDHLNFCI SAFNSSPETD SSKLADSLHQ SLLDMRELLS TQAKL
//
