ID C3ZUG1_BRAFL Unreviewed; 626 AA.
AC C3ZUG1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_92234 {ECO:0000313|EMBL:EEN43800.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN43800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN43800.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN43800.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR EMBL; GG666683; EEN43800.1; -; Genomic_DNA.
DR RefSeq; XP_002587789.1; XM_002587743.1.
DR AlphaFoldDB; C3ZUG1; -.
DR STRING; 7739.C3ZUG1; -.
DR eggNOG; KOG0385; Eukaryota.
DR InParanoid; C3ZUG1; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 2.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR PANTHER; PTHR10799:SF997; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5; 1.
DR Pfam; PF00341; PDGF; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..626
FT /note="Helicase ATP-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002937255"
FT DOMAIN 76..164
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
FT DOMAIN 333..498
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 298..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 626
FT /evidence="ECO:0000313|EMBL:EEN43800.1"
SQ SEQUENCE 626 AA; 70144 MW; C9C56AEB64768991 CRC64;
MSIFTSFVLL SSLVALGATQ RAPSPEESLL TSEIPVEIQR LLRNVTSYEE LKATFNLDIF
TAEDDRFSLT GPPPCIPREM PVPVPLDAEP NVVLWPSCVS VARCGGCCNS DLYECQASRS
SSQVFSVLKL FYSPGNPSSQ PFNNAFDQVQ VERHDQCACV CKNKHLCDLR THFFDDNTCD
CVCRHRGGCV LGAVSDDSCS RQCPSGWKLD EDACQCRLDG RALFGSLGRR CVLGAVSDDS
CSRQCPSGWK LDEDACQCRL DGRALFGSLG RRIQGSRAPG GQCEFEFHLV GNFVKTSNMS
SSSSSPSSPE EQVDDEYQPP GAAPFKLKSP PRGKGIEPKE DKDYEAKVGL GKTLQTISLL
GYMKHYRSIP GPHLVIVPKS TLANWMNEFE HWCPSIRTVS LIGDQEKRAA IIRDQIMPGE
WDVCITSYEM ALREKAVFKK FNWRYLVIDE AHRIKNEKSK LSEIVRTFKT TNRLLLTGTP
LQNNLHELWS LLNFLLPDVF NSSEDFDAWF DTNACLDKDD MVARLHTLSE IVRTFKTTNR
LLLTGTPLQN NLHELWSLLN FLLPDVFNSS EDFDAWFDTN ACLDKDDMVA RLHTYQPPGA
APFKLKSPPR GKGIEPKEDK DYEAKV
//
