ID C3ZUN9_BRAFL Unreviewed; 687 AA.
AC C3ZUN9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=1-alkyl-2-acetylglycerophosphocholine esterase {ECO:0000256|ARBA:ARBA00013201};
DE EC=3.1.1.47 {ECO:0000256|ARBA:ARBA00013201};
GN ORFNames=BRAFLDRAFT_94644 {ECO:0000313|EMBL:EEN43751.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN43751.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN43751.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN43751.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O = 1-O-
CC hexadecyl-sn-glycero-3-phosphate + acetate + H(+);
CC Xref=Rhea:RHEA:41704, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30089, ChEBI:CHEBI:77580, ChEBI:CHEBI:78385;
CC Evidence={ECO:0000256|ARBA:ARBA00035804};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:41705;
CC Evidence={ECO:0000256|ARBA:ARBA00035804};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-
CC O-hexadecyl-sn-glycero-3-phosphocholine + acetate + H(+);
CC Xref=Rhea:RHEA:40479, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30089, ChEBI:CHEBI:44811, ChEBI:CHEBI:64496;
CC Evidence={ECO:0000256|ARBA:ARBA00023721};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:40480;
CC Evidence={ECO:0000256|ARBA:ARBA00023721};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-
CC alkyl-sn-glycero-3-phosphocholine + acetate + H(+);
CC Xref=Rhea:RHEA:17777, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30089, ChEBI:CHEBI:30909, ChEBI:CHEBI:36707; EC=3.1.1.47;
CC Evidence={ECO:0000256|ARBA:ARBA00023737};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:17778;
CC Evidence={ECO:0000256|ARBA:ARBA00023737};
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DR EMBL; GG666684; EEN43751.1; -; Genomic_DNA.
DR RefSeq; XP_002587740.1; XM_002587694.1.
DR AlphaFoldDB; C3ZUN9; -.
DR InParanoid; C3ZUN9; -.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR24401:SF29; DUF6729 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24401; SI:CH211-243P7.3-RELATED; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
FT DOMAIN 230..352
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT REGION 383..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 72808 MW; 8AF25817FD65F6E2 CRC64;
MKYWLAHSWL RRFAEGYGDK MPDKDAINLP SSMTRTGSCN LLPLANGNDV VHIFALPEEQ
LSRSQSWPVG EAPTVLGADV FEIKTVGDLE DIHYHLKENG RINGLNINTA CAKCLQTVSD
IILREKTAGR TFVVLSPYIS FMNDGDTDVT DVAIKECEIV YARIIGDGKP KNLLVGHVEV
VGHVQPSLGS LFPCPEESCV KIILAFTDSI CKYVSNHATF SSDILFSLNA HPGASVYDLT
SDISRHPFVE PDLVFLHAGT NCLPMHRPLS RTLDDFSYLI SVTKSRFPSA SVVISSILPR
FDSEVYDRRR SELNSHLLRL CSSQGVFLLD NGSRARRAMF SVDGLHLSRA GNISYAKYLS
FSLSHYLQLH RRSCQHRFTL RGEEWPGLGT DGRSGKKDKE HPGEEQKSGE YQGQVEWARV
VRQGGPVARP APGKVEGKGP SQPRGVPVAR AAPGKVEGGN AGKGPSQPRG VPVARAAPGK
VEGKGPSQPR GVPVARAAPG KVEGGNAGKG PSQPRGVPVA RAAPGKVEGG NAGKGPSRPR
EVAVASAAPG KVVGCSVGKG PSRPRGVPVA RAAPGKVVGG NAGKGPSRPR GVPVPQPRLP
PGKVEGGSAG KGPSRPRGGP VPKPRVASGK VEGGSVGKGP SRPRGGPVPK PRVASGKVPR
GVQHGTWVWC RPVVSEVWKS SVSTAGC
//
