ID C3ZWY8_BRAFL Unreviewed; 563 AA.
AC C3ZWY8;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Hyaluronan synthase 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_103600 {ECO:0000313|EMBL:EEN42950.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN42950.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN42950.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN42950.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666705; EEN42950.1; -; Genomic_DNA.
DR RefSeq; XP_002586939.1; XM_002586893.1.
DR AlphaFoldDB; C3ZWY8; -.
DR eggNOG; KOG2571; Eukaryota.
DR InParanoid; C3ZWY8; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050501; F:hyaluronan synthase activity; IBA:GO_Central.
DR GO; GO:0085029; P:extracellular matrix assembly; IBA:GO_Central.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IBA:GO_Central.
DR GO; GO:0030213; P:hyaluronan biosynthetic process; IBA:GO_Central.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR22913; HYALURONAN SYNTHASE; 1.
DR PANTHER; PTHR22913:SF12; N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR Pfam; PF13641; Glyco_tranf_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 563 AA; 65673 MW; D5D1C439A0D982B7 CRC64;
MMNWKTVVRI TLTTLFALCL FAGMIVVYAI GFQFVFSGDG YLSFGLYGSV LALHLIIQSI
FAFLEHRKMN RDDLPPHQEK PVALCIAAFQ EDPVLLRKCL ESIRDIKYKN LKVVLVIDGN
SDDDMYMRDT FVEIMGPQDT DTFVWRHNYH AREPLPREIP TLEKGSKHLE DVVAPSLRDN
GAKVVEDIIL NNRNSCIMQK WGGKREVMYT AFRALGDTVE YVQVCDSDTI LEPNCTDEMA
KILDNDRTVG AVGGDVRIWN ERDSWISFLS SLRYWMAFNI ERACQSYFNV VSCISGPLGF
YRNDLLQSFL EDWYNQTFLG QHCTFGDDRH LTNRMLSIGY GTKYTARSRC YTETPVQYLR
WLNQQTRWTK SYFREWLYNA MWFHKHHIWM TYESIIAGLF PFFVTVTVIR LFYRGRLWDI
LLILITIQTI GLIKSFYACF LRRSPTMVFM SIYSILYMTS LLPAKYWAML TINKSGWGTS
GRKKIVTNFI PLVPLIAWAL ILGGGLAYTI YYDTLDYFDY TKQMYLSVGF ALYMVYWFVM
IALYSWRTCK CGCCRDSYTV DEV
//
