ID C4A0E0_BRAFL Unreviewed; 380 AA.
AC C4A0E0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_114042 {ECO:0000313|EMBL:EEN41743.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN41743.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN41743.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN41743.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR EMBL; GG666800; EEN41743.1; -; Genomic_DNA.
DR RefSeq; XP_002585732.1; XM_002585686.1.
DR AlphaFoldDB; C4A0E0; -.
DR STRING; 7739.C4A0E0; -.
DR eggNOG; ENOG502QQ8Z; Eukaryota.
DR InParanoid; C4A0E0; -.
DR GO; GO:0047617; F:acyl-CoA hydrolase activity; IBA:GO_Central.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR PANTHER; PTHR10824:SF4; PROTEIN CBG14567; 1.
DR Pfam; PF08840; BAAT_C; 2.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
FT DOMAIN 15..146
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 192..240
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT DOMAIN 270..372
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 221
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 287
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 321
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 380 AA; 42301 MW; 1EFECC0212D95D3D CRC64;
MQARLLVTPA TALVDDKVDI TVERLAPRQP VTLHARLSEG TARFQSYAHY RADDTGRVVV
AKQPSLGGLY TGVDQMGLFW SMQPSPGQKP GLRLRKKDVS TPFLVDVRVH EGHVDVMGEE
NLPWLATTTV ERWYLGHGVK RVPVREGRIR GTLFLPPGLA EYRAALLASR GFAVLALAFF
AYDDLPKEMV NVDLDYFEEA ADWLLSLPNV QSHGVGVVAT SKGVEIALSM AAHMDKINFL
QTGCCCSRHQ WLHGCNCCST ALQGHSLPLC TVEKARCPIM FVAAEDDLST KAVFFANQAI
DRMKAHGKTN YTLLQYPKAG HLIEPPYSPH CALYYHRVFD WCMLAGGEPR SHAAAQEDSW
HKILSFFRTH VDKNSTQSRL
//
