ID C4ICC2_CLOBU Unreviewed; 278 AA.
AC C4ICC2;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Nitroreductase family protein {ECO:0000313|EMBL:EEP56342.1};
GN ORFNames=CLP_0797 {ECO:0000313|EMBL:EEP56342.1};
OS Clostridium butyricum E4 str. BoNT E BL5262.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP56342.1, ECO:0000313|Proteomes:UP000003081};
RN [1] {ECO:0000313|EMBL:EEP56342.1, ECO:0000313|Proteomes:UP000003081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the nitroreductase family.
CC {ECO:0000256|ARBA:ARBA00007118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP56342.1}.
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DR EMBL; ACOM01000001; EEP56342.1; -; Genomic_DNA.
DR RefSeq; WP_003413410.1; NZ_ACOM01000001.1.
DR AlphaFoldDB; C4ICC2; -.
DR STRING; 1492.ATN24_18930; -.
DR GeneID; 66379146; -.
DR eggNOG; COG0778; Bacteria.
DR eggNOG; COG1145; Bacteria.
DR HOGENOM; CLU_070764_2_1_9; -.
DR Proteomes; UP000003081; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02143; nitroreductase_FeS-like; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR PANTHER; PTHR43673; NAD(P)H NITROREDUCTASE YDGI-RELATED; 1.
DR PANTHER; PTHR43673:SF10; PROTEIN DRGA; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000003081}.
FT DOMAIN 1..29
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 30..58
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 278 AA; 31461 MW; A66D7F5B2665FCBE CRC64;
MFKVNKDKCI GCSQCVKDCP VRVISLIDNK AEINNNNCMK CGHCIAICPV NAVSTDDYNM
EEVISYDKNS FSVDPDNLLN FIKFRRSVRK FKDKKVEKDT ISKIIDAGRF TQTSTNSQDV
SYTVITEKLD ELKALTYESL KNKGESILAS LTDKNLTKET ERLKRYARIW MYMYAEYKKD
PVKNDRLFFN APLAIVVTSP TPINAGLASS NMELMTDALG LGTFFSGFFV VASQDNKEIL
DLLGIEDSKQ IATCLVIGYP DVKYQRTAPR KDAEINWI
//
