ID   C4IGD0_CLOBU            Unreviewed;       224 AA.
AC   C4IGD0;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   SubName: Full=Haloacid dehalogenase, type II {ECO:0000313|EMBL:EEP53530.1};
DE            EC=3.8.1.2 {ECO:0000313|EMBL:EEP53530.1};
GN   Name=dehII {ECO:0000313|EMBL:EEP53530.1};
GN   ORFNames=CLP_1835 {ECO:0000313|EMBL:EEP53530.1};
OS   Clostridium butyricum E4 str. BoNT E BL5262.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP53530.1, ECO:0000313|Proteomes:UP000003081};
RN   [1] {ECO:0000313|EMBL:EEP53530.1, ECO:0000313|Proteomes:UP000003081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA   Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA   Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA   Smith T.J., Sutton G., Brettin T.;
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. S-2-
CC       haloalkanoic acid dehalogenase family. {ECO:0000256|ARBA:ARBA00008106}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEP53530.1}.
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DR   EMBL; ACOM01000005; EEP53530.1; -; Genomic_DNA.
DR   RefSeq; WP_003414651.1; NZ_ACOM01000005.1.
DR   AlphaFoldDB; C4IGD0; -.
DR   eggNOG; COG1011; Bacteria.
DR   HOGENOM; CLU_045011_3_1_9; -.
DR   Proteomes; UP000003081; Unassembled WGS sequence.
DR   GO; GO:0018784; F:(S)-2-haloacid dehalogenase activity; IEA:UniProtKB-EC.
DR   CDD; cd02588; HAD_L2-DEX; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   InterPro; IPR006328; 2-HAD.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006439; HAD-SF_hydro_IA.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR023198; PGP-like_dom2.
DR   NCBIfam; TIGR01493; HAD-SF-IA-v2; 1.
DR   NCBIfam; TIGR01428; HAD_type_II; 1.
DR   PANTHER; PTHR43316:SF3; HALOACID DEHALOGENASE, TYPE II (AFU_ORTHOLOGUE AFUA_2G07750)-RELATED; 1.
DR   PANTHER; PTHR43316; HYDROLASE, HALOACID DELAHOGENASE-RELATED; 1.
DR   Pfam; PF00702; Hydrolase; 1.
DR   PRINTS; PR00413; HADHALOGNASE.
DR   SFLD; SFLDF00045; 2-haloacid_dehalogenase; 1.
DR   SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:EEP53530.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003081}.
SQ   SEQUENCE   224 AA;  26341 MW;  0D54D639E44ACF10 CRC64;
     METLKNTKLC VFDAYGTLFD INSVTKQYCN ELEEISDQFS NLWRSKQLEY TWLRSLMNRY
     EDFWCITEES LDYTLKYFNI KNDFLKSNLL KSYENINCYE EVPKTLFKLK EKGLLIIILS
     NASPTMLQMA VKNSNLNFLI TDCITVDSVK IYKPHATVYN LVLEKYNFKK NEILFVSSNS
     WDVAGAKSFG LNVAWINRFD NKKEFLPFEP DIELKSLMDL PNII
//