ID   C4JIV0_UNCRE            Unreviewed;       550 AA.
AC   C4JIV0;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   RecName: Full=Peroxisomal targeting signal receptor {ECO:0000256|ARBA:ARBA00014710};
DE   AltName: Full=Peroxin-5 {ECO:0000256|ARBA:ARBA00032505};
GN   ORFNames=UREG_01557 {ECO:0000313|EMBL:EEP76708.1};
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP76708.1, ECO:0000313|Proteomes:UP000002058};
RN   [1] {ECO:0000313|Proteomes:UP000002058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- SUBUNIT: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting
CC       translocation through the PEX13-PEX14 docking complex.
CC       {ECO:0000256|ARBA:ARBA00038659}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix
CC       {ECO:0000256|ARBA:ARBA00004253}.
CC   -!- SIMILARITY: Belongs to the peroxisomal targeting signal receptor
CC       family. {ECO:0000256|ARBA:ARBA00005348}.
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DR   EMBL; CH476615; EEP76708.1; -; Genomic_DNA.
DR   RefSeq; XP_002542041.1; XM_002541995.1.
DR   AlphaFoldDB; C4JIV0; -.
DR   STRING; 336963.C4JIV0; -.
DR   GeneID; 8440973; -.
DR   KEGG; ure:UREG_01557; -.
DR   VEuPathDB; FungiDB:UREG_01557; -.
DR   eggNOG; KOG1125; Eukaryota.
DR   HOGENOM; CLU_013516_3_0_1; -.
DR   InParanoid; C4JIV0; -.
DR   OMA; WEEQFKQ; -.
DR   OrthoDB; 2020042at2759; -.
DR   Proteomes; UP000002058; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005782; C:peroxisomal matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR024111; PEX5/PEX5L.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR001440; TPR_1.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR10130:SF0; GH08708P; 1.
DR   PANTHER; PTHR10130; PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5; 1.
DR   Pfam; PF00515; TPR_1; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 2.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   3: Inferred from homology;
KW   Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Receptor {ECO:0000313|EMBL:EEP76708.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW   Thioester bond {ECO:0000256|ARBA:ARBA00022966};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}; Translocation {ECO:0000256|ARBA:ARBA00023010};
KW   Transport {ECO:0000256|ARBA:ARBA00022448};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   REPEAT          378..411
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          420..453
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   550 AA;  60735 MW;  6D7D07C07D23E829 CRC64;
     MSFLGGAECS SAGNPLTQFA KHVQNDKSLQ RDRLVSRGTN GLQDGMRTRG IVGGPDYMMD
     EFMQQAELMA PAAAQPFTMG QMRRELENLH TSPQQRAGSP AWAAEFDPGE SARMEAAFPG
     AKLQMIKGAG FSPSEFTHFS QQIEAQRAAS SVTTAVPVTS AYQSHTGIGY RGLGGGYMNM
     MGPSYGPVGM QQQAPMQEDK GKGRMIELDD KNWEAQFAAI DAVGEKALDG EANAAMEAEL
     DSLDRSVPNE SDAFDDFESI WRGIQTETAG HRQMAHEELN MENMHMGDFG EWDNFDLGLN
     THSFRDPQLG DYLFEEDNNY RLNSNPFEEG MRMMREGDNL SLAVLAFEAA VQRDPKHKVT
     DLFIRAAQLS PQGEHMDPDV QVGLGVLFYG AEEYDKAVDC FSAALASNES GTSNQEEQVH
     LLWNRLGATL ANSGRSEEAI EAYEKALTVR PNFVRARYNL GVSCINIGCY PEAAQHLLGA
     LAMHQAVDHL ESPPFPATAS EDADLHTTHN QSTNLYDTLR RVFNQMGRRD LSDMVVNGMD
     VEVFRKEFTF
//