ID C4KAJ8_THASP Unreviewed; 476 AA.
AC C4KAJ8;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACR01424.1};
GN OrderedLocusNames=Tmz1t_2825 {ECO:0000313|EMBL:ACR01424.1};
OS Thauera aminoaromatica.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=164330 {ECO:0000313|EMBL:ACR01424.1, ECO:0000313|Proteomes:UP000002186};
RN [1] {ECO:0000313|Proteomes:UP000002186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MZ1T {ECO:0000313|Proteomes:UP000002186};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Sayler G.S.;
RT "Complete sequence of chromosome of Thauera sp. MZ1T.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACR01424.1, ECO:0000313|Proteomes:UP000002186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MZ1T {ECO:0000313|EMBL:ACR01424.1,
RC ECO:0000313|Proteomes:UP000002186};
RX PubMed=23407619; DOI=10.4056/sigs.2696029;
RA Jiang K., Sanseverino J., Chauhan A., Lucas S., Copeland A., Lapidus A.,
RA Del Rio T.G., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D.,
RA Brettin T., Detter J.C., Han C., Chang Y.J., Larimer F., Land M.,
RA Hauser L., Kyrpides N.C., Mikhailova N., Moser S., Jegier P., Close D.,
RA Debruyn J.M., Wang Y., Layton A.C., Allen M.S., Sayler G.S.;
RT "Complete genome sequence of Thauera aminoaromatica strain MZ1T.";
RL Stand. Genomic Sci. 6:325-335(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001281; ACR01424.1; -; Genomic_DNA.
DR AlphaFoldDB; C4KAJ8; -.
DR STRING; 85643.Tmz1t_2825; -.
DR KEGG; tmz:Tmz1t_2825; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_4_4; -.
DR Proteomes; UP000002186; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002186}.
FT DOMAIN 117..392
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 232..283
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 476 AA; 49885 MW; 7BF8E22FDAF8EEDE CRC64;
MGVPAASALP CPDLRAPSAE PRRTCPSRSA PAGRHDAALV PAAANPARGI DSGATIILNT
PGKTPDDPLR AGRPSTLRRL LGSRAGVGAG VLAISALAFA TFHHETVNVA LVEEGPLRQA
IVASGRVRTP ERIVVSAQIA GRVQAVEVRE GDALAPGQAL LRLDEREWGA AVAQAGAAVV
QGEARLRQLR ELGLPVAEQA LRQAEATALQ AQRHHRRVQE LVARGFYSQA QLDEARRALD
VADSQVRSAR LQRASQQPGG SEIELARSAL EQARAALAAA ETRLSYATLR APVAGTVLTR
NVEAGDTVQP GTPLMTIAPA GATELTVQID EKNLALLHPG QAALASADAY PGERFAAVLA
YIAPSVDAQR GSVEVRLRVP EPPPYLRHEM TVSLDIEAAR RERTLAVPAA AVRESGGAQP
WVLVVRDGRT ARQPVRLGIR GAGRVEVLEG LAAGEAVVPA PADVPAGRAV RTRVQP
//
