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Database: UniProt
Entry: C4LVX3_ENTHI
LinkDB: C4LVX3_ENTHI
Original site: C4LVX3_ENTHI 
ID   C4LVX3_ENTHI            Unreviewed;       536 AA.
AC   C4LVX3;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   31-JAN-2018, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAL51106.1};
GN   ORFNames=EHI_125870 {ECO:0000313|EMBL:EAL51106.1};
OS   Entamoeba histolytica.
OC   Eukaryota; Amoebozoa; Archamoebae; Entamoebidae; Entamoeba.
OX   NCBI_TaxID=5759 {ECO:0000313|EMBL:EAL51106.1, ECO:0000313|Proteomes:UP000001926};
RN   [1] {ECO:0000313|EMBL:EAL51106.1, ECO:0000313|Proteomes:UP000001926}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 30459 / HM-1:IMSS {ECO:0000313|Proteomes:UP000001926};
RX   PubMed=15729342; DOI=10.1038/nature03291;
RA   Loftus B.J., Anderson I., Davies R., Alsmark U.C., Samuelson J.,
RA   Amedeo P., Roncaglia P., Berriman M., Hirt R.P., Mann B.J., Nozaki T.,
RA   Suh B., Pop M., Duchene M., Ackers J., Tannich E., Leippe M.,
RA   Hofer M., Bruchhaus I., Willhoeft U., Bhattacharya A.,
RA   Chillingworth T., Churcher C.M., Hance Z., Harris B., Harris D.,
RA   Jagels K., Moule S., Mungall K.L., Ormond D., Squares R.,
RA   Whitehead S., Quail M.A., Rabbinowitsch E., Norbertczak H., Price C.,
RA   Wang Z., Guillen N., Gilchrist C., Stroup S.E., Bhattacharya S.,
RA   Lohia A., Foster P.G., Sicheritz-Ponten T., Weber C., Singh U.,
RA   Mukherjee C., El-Sayed N.M.A., Petri W.A., Clark C.G., Embley T.M.,
RA   Barrell B.G., Fraser C.M., Hall N.;
RT   "The genome of the protist parasite Entamoeba histolytica.";
RL   Nature 433:865-868(2005).
RN   [2] {ECO:0000313|EMBL:EAL51106.1, ECO:0000313|Proteomes:UP000001926}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 30459 / HM-1:IMSS {ECO:0000313|Proteomes:UP000001926};
RA   Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS571160; EAL51106.1; -; Genomic_DNA.
DR   RefSeq; XP_656491.1; XM_651399.1.
DR   EnsemblProtists; GAT92831; GAT92831; CL6EHI_125870.
DR   EnsemblProtists; rna_EHI_125870-1; rna_EHI_125870-1; EHI_125870.
DR   GeneID; 3410814; -.
DR   KEGG; ehi:EHI_125870; -.
DR   EuPathDB; AmoebaDB:EHI_125870; -.
DR   InParanoid; C4LVX3; -.
DR   OMA; CDNIESI; -.
DR   Proteomes; UP000001926; Partially assembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0004175; F:endopeptidase activity; IBA:GO_Central.
DR   GO; GO:0016485; P:protein processing; IBA:GO_Central.
DR   InterPro; IPR008710; Nicastrin.
DR   PANTHER; PTHR21092; PTHR21092; 1.
DR   Pfam; PF05450; Nicastrin; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001926};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001926};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    536       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5012858797.
FT   TRANSMEM    509    531       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   536 AA;  60971 MW;  F0DA86D016B15494 CRC64;
     MIELLLLFFL FYCYSEKIDL KKNRLDVVKD KLNNVIDSTT AYLLLNNDKM IGSYGRKKLI
     NGKVIHLPTE EEIQIWKKSN DYNGILVVPD HLLDSTHLNL FEQLKVQGVV FYDSNSTHYV
     SQDYRSSFNP NASEVAWKKY TYPIMFTPTS IVYFTQNNGY LQIEDEMLAD GDSEICLRRG
     MCQPIGGQSL VGRLVENHLS ESILLSAQLD GVSIFRDATP AHEQIVSGEA TLLSVLETLR
     PLMKGAKKGI DFGFFEGETF GNMGSKTFSK SNDSYSHIIH FGPLGLTEGS LFVYSKDQVP
     QDIHKRIVNK TNEYPHCALS SFKNGIKMYL SDHEELYKGN IGTHQDYLPY ITELCDNIES
     ITQIILQIIF NRSDIETLQK ELEIQYDCEK YHRLYHCLAY DLSCDYFNET IGIIQGNSNS
     YSSIYRETKI TPRSKAIHDY LNRIVTMGVC KEECDTSIKN GTVTYLGSYG SDIDISKNKV
     VGSSGDAWTE SNWKQVKLTF YQPRTFGDVT LITLGVGLTL MTIIAFFTVI FKLNLL
//
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