ID C4QYE6_KOMPG Unreviewed; 294 AA.
AC C4QYE6;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE SubName: Full=Mitochondrial protein, putative inner membrane transporter {ECO:0000313|EMBL:CAY68269.1};
GN OrderedLocusNames=PAS_chr1-4_0420 {ECO:0000313|EMBL:CAY68269.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY68269.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY68269.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN392319; CAY68269.1; -; Genomic_DNA.
DR RefSeq; XP_002490550.1; XM_002490505.1.
DR AlphaFoldDB; C4QYE6; -.
DR SMR; C4QYE6; -.
DR EnsemblFungi; CAY68269; CAY68269; PAS_chr1-4_0420.
DR GeneID; 8197008; -.
DR KEGG; ppa:PAS_chr1-4_0420; -.
DR eggNOG; KOG0758; Eukaryota.
DR HOGENOM; CLU_015166_16_2_1; -.
DR InParanoid; C4QYE6; -.
DR OMA; VWFLAFE; -.
DR OrthoDB; 4064096at2759; -.
DR Proteomes; UP000000314; Chromosome 1.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 2.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45624; MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR45624:SF12; MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN S-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT REPEAT 10..92
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 104..190
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 202..291
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 294 AA; 32317 MW; CBD41914F282372E CRC64;
MSQEVDESLL RKAKDVTAGF AGGAVQVLIG QPFDLVKVRL QTGQYNSPLT AVKDTLKNEG
LLAFYKGTLA PLFGVGACVS LQFYGFHEAK RQLLKYNSDN SGTLSLPQFY AAGAVAGIVN
TPITAPVEQL RIILQTQKGK SGYHGPRELV KHIVRENGFS ALGRGFQITL LREIQAYGVW
FLAYEWLMKT TTEKWGIARD QISTPQLMLY GALAGEFLWL GSYPLDVIKS RVQGDTFGST
SKYHGSARAA ARHIWQTQGL IGFWRGIVPT LVRAIPCSAA TFTTVEWTLR LLGN
//
