ID C4R374_KOMPG Unreviewed; 500 AA.
AC C4R374;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Sorting nexin {ECO:0000313|EMBL:CAY71208.1};
GN OrderedLocusNames=PAS_chr3_1139 {ECO:0000313|EMBL:CAY71208.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY71208.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY71208.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; FN392321; CAY71208.1; -; Genomic_DNA.
DR RefSeq; XP_002493387.1; XM_002493342.1.
DR AlphaFoldDB; C4R374; -.
DR STRING; 644223.C4R374; -.
DR EnsemblFungi; CAY71208; CAY71208; PAS_chr3_1139.
DR GeneID; 8200171; -.
DR KEGG; ppa:PAS_chr3_1139; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_035999_0_0_1; -.
DR InParanoid; C4R374; -.
DR OMA; DFKDPWG; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT DOMAIN 1..121
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 500 AA; 58317 MW; 51A8D000D2F247E3 CRC64;
MDQDDTIFII TTETFRDIKR QSTVYYTIRS KYGIVKRRYT DFYSLRKCLC KMYPTKPVPP
IPEKHSFKKL ISKPLSYKND PATINLRTRL LGSFLNNLTQ ELVFRESIMV IRFLDPDERN
WAEALKTPPF TSLPQSIFLS SPRSPLQPNP YHSYFPIPPL SLVKNFDSPL NQEFRPSELF
FRRILKYLTH LHKLNKHFEN DLHRYNKQLV GLGGSLNIFS LIDTTISKSN GTTLDENNSI
EGVGQSVDSS FINLERFILH FVANFKEPIM ELRSFCMVII NLLQYRKLKE LQLCYLKRII
VKKQTRTQRL LDIERLSQKL DIALQQGASQ SPTIANAIRN LEAQPSVYQS VYFDPKSYAD
DEDSSAEGVN NLVASDIVDD EDNYSMSDNN SINLNSSALF HEYKDQRVWN MFSKVTKNIQ
AMTPLERSLE IQANCRDLQK LVHCFQLLND DVTFVSIEIE KSTLRERQYV KDRFLELLEN
FKMILCIYSR SNQIAWENGI
//
