ID C4T9W9_STRHY Unreviewed; 366 AA.
AC C4T9W9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:BAH67055.1};
DE Flags: Fragment;
OS Streptomyces hygroscopicus subsp. enhygrus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX NCBI_TaxID=285529 {ECO:0000313|EMBL:BAH67055.1};
RN [1] {ECO:0000313|EMBL:BAH67055.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 13978 {ECO:0000313|EMBL:BAH67055.1};
RA Komaki H., Tamura T., Otoguro M., Nakashima T., Harayama S.;
RT "Partial sequencing of type-I polyketide synthase genes in Streptomyces and
RT the application for metabolite prediction by phylogenetic analysis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB431016; BAH67055.1; -; Genomic_DNA.
DR AlphaFoldDB; C4T9W9; -.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Transferase {ECO:0000256|ARBA:ARBA00023315}.
FT DOMAIN 1..366
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAH67055.1"
FT NON_TER 366
FT /evidence="ECO:0000313|EMBL:BAH67055.1"
SQ SEQUENCE 366 AA; 38632 MW; 2EE6708EAD70A74A CRC64;
LEALYDPDPE TQGTSYAREG GFLHDAAEFD PAFFGISPRE ALAMDPQQRL LLETPWEAFE
RAGIDPLSVR GSRTGVFAGV MYHNYGSRLH AVPNEVEGYL GTGSSSSVVS GRVAYTFGLE
GPAVTVDTAC SSSLVALHLA AQALRQGECS LALAGGVTVM FTPGTFIDFS RQRGLARDGR
CKSFAAAADG TGWGEGAGML LLERLSDARR NGHEVLAIVR GSAVNQDGAS NGLTAPNGPS
QQRVIRQALA NARLTTGEVD AVEAHGTGTT LGDPIEAQAL LATHGQERDA ERPLWLGSVK
SNLGHTQAAS GVAGIIKMVL SMRHGVLPRT LHVDEPSPHV DWSAGAVSLL TEQMEWPETG
RPRRAA
//
