ID C4TAL1_STRCU Unreviewed; 365 AA.
AC C4TAL1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:BAH67297.1};
DE Flags: Fragment;
OS Streptomyces collinus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=42684 {ECO:0000313|EMBL:BAH67297.1};
RN [1] {ECO:0000313|EMBL:BAH67297.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 12759 {ECO:0000313|EMBL:BAH67297.1};
RA Komaki H., Tamura T., Otoguro M., Nakashima T., Harayama S.;
RT "Partial sequencing of type-I polyketide synthase genes in Streptomyces and
RT the application for metabolite prediction by phylogenetic analysis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; AB431258; BAH67297.1; -; Genomic_DNA.
DR AlphaFoldDB; C4TAL1; -.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Transferase {ECO:0000256|ARBA:ARBA00023315}.
FT DOMAIN 1..365
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAH67297.1"
FT NON_TER 365
FT /evidence="ECO:0000313|EMBL:BAH67297.1"
SQ SEQUENCE 365 AA; 38313 MW; C52E54691355D57C CRC64;
VDGLYDPDPD RTGTSYAREG GFLYDADRFD PAFFGMSPRE AMAIDPQQRL LLETAWEAFE
HAGIDATALR GSDTGVFTGQ MYNDYGSRPH LPPEDFEGYL FSGSAGSIAV GRLSYTYGFE
GPAVSVDTAC SSSLVALHLA VNALRGGECS LALAGGVTVM STPVAFLEFS RLRGLSPDGR
CKSFAAGADG VAWAEGAGVL VVERLSDAVR NGHRVLAVVR GSAVNQDGAS NGLTAPNGPS
QERVIRQALA SAGLSASEVD AVEAHGTGTR LGDPIEAQAL LATYGQDREQ PLLLGSLKSN
IGHAQAAAGV GGVIKMVQAM RHGVLPRTLH VDEPSPFVEW DTGAVELLTE AREWPAREDA
PRRAG
//
