ID   C4TLE4_9HIV1            Unreviewed;       105 AA.
AC   C4TLE4;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Pol polyprotein {ECO:0000313|EMBL:BAH60251.1};
DE   Flags: Fragment;
GN   Name=pol {ECO:0000313|EMBL:BAH60251.1};
OS   Human immunodeficiency virus 1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11676 {ECO:0000313|EMBL:BAH60251.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:BAH60251.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=3761700 {ECO:0000313|EMBL:BAH60251.1};
RA   Kawashima Y., Pfafferott K., Frater J., Matthews P., Payne R., Addo M.,
RA   Gatanaga H., Fujiwara M., Hachiya A., Koizumi H., Kuse N., Oka S., Duda A.,
RA   Prendergast A., Crawford H., Leslie A., Brumme Z., Brumme C., Allen T.,
RA   Brander C., Kaslow R., Tang J., Hunter E., Allen S., Mulenga J., Branch S.,
RA   Roach T., John M., Mallal S., Ogwu A., Shapiro R., Prado J.G., Fidler S.,
RA   Weber J., Pybus O.G., Klenerman P., Ndung'u T., Phillips R., Heckerman D.,
RA   Harrigan P.R., Walker B.D., Takiguchi M., Goulder P.;
RT   "Adaptation of HIV-1 to human leukocyte antigen class I.";
RL   Nature 458:641-645(2009).
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DR   EMBL; AB475750; BAH60251.1; -; Genomic_RNA.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR41694; ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN; 1.
DR   PANTHER; PTHR41694:SF3; RNA-DIRECTED DNA POLYMERASE-RELATED; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral release from host cell {ECO:0000256|ARBA:ARBA00023113};
KW   Virion maturation {ECO:0000256|ARBA:ARBA00023113}.
FT   DOMAIN          1..105
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAH60251.1"
FT   NON_TER         105
FT                   /evidence="ECO:0000313|EMBL:BAH60251.1"
SQ   SEQUENCE   105 AA;  12372 MW;  81FE1D8245F3E2DB CRC64;
     LDVGDAYFSV PLDKEFRKYT AFTIPSLNNE TPGIRYQYNV LPQGWKGSPA IFQCSMTKIL
     EPFRKQNPEI VIYQYMDDLY VGSDLEIEQH RTKIEELRQH LLKWG
//