GenomeNet

Database: UniProt
Entry: C4XFM3_MYCFP
LinkDB: C4XFM3_MYCFP
Original site: C4XFM3_MYCFP 
ID   C4XFM3_MYCFP            Unreviewed;       471 AA.
AC   C4XFM3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   25-OCT-2017, entry version 59.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   OrderedLocusNames=MBIO_0680 {ECO:0000313|EMBL:BAH69945.1};
OS   Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 /
OS   PG18).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=496833 {ECO:0000313|EMBL:BAH69945.1, ECO:0000313|Proteomes:UP000006810};
RN   [1] {ECO:0000313|EMBL:BAH69945.1, ECO:0000313|Proteomes:UP000006810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18
RC   {ECO:0000313|Proteomes:UP000006810};
RX   PubMed=19219498; DOI=10.1007/s00284-009-9362-6;
RA   Ishida N., Irikura D., Matsuda K., Sato S., Asano K.;
RT   "Molecular cloning and expression of a novel cholinephosphotransferase
RT   involved in glycoglycerophospholipid biosynthesis of Mycoplasma
RT   fermentans.";
RL   Curr. Microbiol. 58:535-540(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP009608; BAH69945.1; -; Genomic_DNA.
DR   ProteinModelPortal; C4XFM3; -.
DR   STRING; 496833.MBIO_0680; -.
DR   EnsemblBacteria; BAH69945; BAH69945; MBIO_0680.
DR   KEGG; mfp:MBIO_0680; -.
DR   PATRIC; fig|496833.3.peg.272; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   Proteomes; UP000006810; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006810};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006810}.
FT   DOMAIN      156    288       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      376    445       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   471 AA;  54453 MW;  EF0DFE9724794633 CRC64;
     MMAENKNIKD SITMKANTLT FLKSLSSDVN DQMLFKNFIS NFTIVGIDQN NHVKIQTWLQ
     KPSLEILIKM LDGNILKALE ETFERECTYE FVHIPKPIVK LTKASSNKTI SSKTIEEEVK
     LGVDLNKELT FDNYVESDFN KDAIKLANYL VKGGKEYNPI FIYAKSGLGK THLLHAIGNK
     LQEQGKVVKY INPSIYARDI SFYLQENDQA KLKKIKDEFD NADYLIFDDF QSYGVGNKKA
     TIQTIYNILD YRLNTNKTTI FCSDKPINNL NAMFDERLIS RLYMGLQLEI KIPQQSDLLR
     VLDYMLDIND MNPEAWEKEA KNFVTRNYST SIRTLIGAIT RLKFYKMEMA RTNSKYTVAV
     VNSILKDMQQ TKENITPDSI IEYVAKYYKI PKKEILGKSR QKDVVLARHI AIYVIRTQLE
     VPLEQIGHIF GNRDHSTIIN AIRKIETESD MPDKTIKRTI SMISDDIYKL K
//
DBGET integrated database retrieval system