ID   C4Y0U8_CLAL4            Unreviewed;       528 AA.
AC   C4Y0U8;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN   ORFNames=CLUG_01830 {ECO:0000313|EMBL:EEQ37707.1};
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ37707.1, ECO:0000313|Proteomes:UP000007703};
RN   [1] {ECO:0000313|EMBL:EEQ37707.1, ECO:0000313|Proteomes:UP000007703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ37707.1,
RC   ECO:0000313|Proteomes:UP000007703};
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA   Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA   Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA   Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA   Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA   Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA   Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC       ECO:0000256|RuleBase:RU000682}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH408077; EEQ37707.1; -; Genomic_DNA.
DR   RefSeq; XP_002618371.1; XM_002618325.1.
DR   AlphaFoldDB; C4Y0U8; -.
DR   STRING; 306902.C4Y0U8; -.
DR   GeneID; 8498375; -.
DR   KEGG; clu:CLUG_01830; -.
DR   VEuPathDB; FungiDB:CLUG_01830; -.
DR   HOGENOM; CLU_028430_0_0_1; -.
DR   InParanoid; C4Y0U8; -.
DR   OrthoDB; 5401018at2759; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   PANTHER; PTHR24324:SF12; HOMEOBOX DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24324; HOMEOBOX PROTEIN HHEX; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000007703}.
FT   DOMAIN          3..63
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        5..64
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          21..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          509..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   528 AA;  59285 MW;  51BCF6A28ABE7C83 CRC64;
     MAEETSTKRT RASGEVLDYL LREFDSNPNP SPDQRKEISE RTNMSEKAVR IWFQNRRAKV
     RKFERMGKPV KHGGSNVSSR SNSLTQVSAA GLRAQGMIPI ELNENYCFID CSSLSVGSWQ
     RIKSGQHNGA TLSRSLVNLS PFTLNSVMEN VDLMVILSRK NHEINYFFSA ISNNSKILFR
     IFYPISSVLH SSILDSSLSK ENNEMRLNLA RKPKFSVYFF NGVNANLNQW SICDDFSEGQ
     QVSSAFYAPG GTSTPHVLVG AKNSLQFLNN YILSNQLSQK EYAGVSETIT PLAATGSPRA
     DGLPNNMIHS QNHNDDYQIK QDVSSWEDTP HSEKPYASKG LTLIANFEDT SPMSSGSHES
     PGVIKSRYNE EKQMHISSLG VNQPERKEYE EMFSATTPDF FNTVQTPNSN FLPHVSKNEG
     SHFINSPSMG IESYENDSQL EKNSHSRQEN VDIHRPENEY NQGSHDMANT YEADSGYHPQ
     QVEHHYDFES NDFHPNELII NSPALSNGTP NTASSNAHVD NFIDFNAH
//