ID C4Y276_CLAL4 Unreviewed; 319 AA.
AC C4Y276;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 13-SEP-2023, entry version 48.
DE RecName: Full=Dihydroxy-acid dehydratase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CLUG_01217 {ECO:0000313|EMBL:EEQ37094.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ37094.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ37094.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ37094.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC {ECO:0000256|ARBA:ARBA00006486}.
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DR EMBL; CH408077; EEQ37094.1; -; Genomic_DNA.
DR RefSeq; XP_002617758.1; XM_002617712.1.
DR AlphaFoldDB; C4Y276; -.
DR STRING; 306902.C4Y276; -.
DR GeneID; 8499497; -.
DR KEGG; clu:CLUG_01217; -.
DR VEuPathDB; FungiDB:CLUG_01217; -.
DR HOGENOM; CLU_014271_0_0_1; -.
DR InParanoid; C4Y276; -.
DR OMA; KEECHRA; -.
DR OrthoDB; 238at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR InterPro; IPR037237; IlvD/EDD_N.
DR PANTHER; PTHR21000; DIHYDROXY-ACID DEHYDRATASE DAD; 1.
DR PANTHER; PTHR21000:SF5; DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL; 1.
DR Pfam; PF00920; ILVD_EDD; 1.
DR SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR PROSITE; PS00886; ILVD_EDD_1; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703}.
SQ SEQUENCE 319 AA; 33916 MW; F4473EA2231DCC5F CRC64;
MLYATGFKTE DMDKAQIGVG SVWWSGNPCN MHLMDLNDQC TDSVNKAGLK GMQFNSIGVS
DGITNGTEGM KFSLQSREII ADSFETLIMA QMYDGSIAIP SCDKNMPGVL MAMGRHNRPS
LMVYGGTILP GSPSCGATAE IPDKIDIISA FQSYGQYLSD QITEEQRMDV VQHACPGPGA
CGGMYTANTM ASAAEVMGMT LPFSSSAPAV SKEKAAECAS VGEAIKNLLK LDLKPREIMT
KKAFENAITY IIATGGSTNA VLHIIAIASS VGIEITVDDF QRLSDNTPLL ADFKPSGKYV
MADLQTVGRN SSSDENVVG
//
