ID C4Y2L4_CLAL4 Unreviewed; 710 AA.
AC C4Y2L4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=Pre-mRNA-splicing factor CLF1 {ECO:0000256|ARBA:ARBA00039167};
GN ORFNames=CLUG_02777 {ECO:0000313|EMBL:EEQ38651.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ38651.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ38651.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ38651.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the crooked-neck family.
CC {ECO:0000256|ARBA:ARBA00008644}.
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DR EMBL; CH408078; EEQ38651.1; -; Genomic_DNA.
DR RefSeq; XP_002617333.1; XM_002617287.1.
DR AlphaFoldDB; C4Y2L4; -.
DR STRING; 306902.C4Y2L4; -.
DR GeneID; 8497644; -.
DR KEGG; clu:CLUG_02777; -.
DR VEuPathDB; FungiDB:CLUG_02777; -.
DR HOGENOM; CLU_011554_1_0_1; -.
DR InParanoid; C4Y2L4; -.
DR OMA; HIKVWIS; -.
DR OrthoDB; 5479069at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045075; Syf1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR11246:SF3; CROOKED NECK-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR SMART; SM00386; HAT; 11.
DR SUPFAM; SSF48452; TPR-like; 4.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022728};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 83609 MW; 5C6BFC77762A9F1A CRC64;
MSNISLPPNL ATDSASVPVG EVSEKQVTSA DILNEANQLK SSTYKRPEQT IQDLEELRSY
QLSKRREFEQ QLNKNRLNFG QWMRYAKWEV DHNHDFKRAR SIMERALEVN VQHVPFWVRY
IELELLHHNV NHARNLLDRA VTTLPKVDKL WFMYVQTEEA LGNFRGTRSV FERWLTWRPP
KVAWTAYVEF EQRYEEWANA RNIYLRYVSL FPGDADMWLD WLVFETTQPP LDDVQIARIR
GIFECAMDTL IAQEDFKEKT TVASLVARWC SWEASMREFA RARAIYTTLL EKDYLSKTQK
AEVFQSFSEF EKKYGTSAST SETLLLKRKL QYEQNVDVNP KDYESWWELA KLEQDPVRAN
SILENAVQTS PDAVSKSIVW RRYVFLWIKL ALSLEFDCKN LDKARETWKK ALDTVPHTKF
SFAKLWIHYA EFELRHRGLS AARKVLGRAI GQTSQKSPKR KIFRYYIALE QKLAEWDRVR
KLYEKWLESA LIADYNQKTT LALPVLEEYV AFEQRMGESE RCVALYDMAM SITTSPESEL
SFLPFQDLLS VYIDYLKEEF MYDKARQVYR EVLDTKPSVE VWIAFAIFES SILSPSQMDQ
LEQIEEDTHF AIGEYQLSQT RKVFGEAYNK YKATGDGENA LQLLEAWKSY EEMHGTTQSL
ADVEKKTPTQ IRKRRQVDNV EEIYTEYVFP EIKPNISQFL ANAKKWAESE
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