ID C4YCC2_CLAL4 Unreviewed; 278 AA.
AC C4YCC2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DASH complex subunit DAM1 {ECO:0000256|ARBA:ARBA00020497};
DE AltName: Full=Outer kinetochore protein DAM1 {ECO:0000256|ARBA:ARBA00030453};
GN ORFNames=CLUG_05761 {ECO:0000313|EMBL:EEQ41633.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ41633.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ41633.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ41633.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DASH complex DAM1 family.
CC {ECO:0000256|ARBA:ARBA00010073}.
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DR EMBL; CH408083; EEQ41633.1; -; Genomic_DNA.
DR RefSeq; XP_002614275.1; XM_002614229.1.
DR AlphaFoldDB; C4YCC2; -.
DR STRING; 306902.C4YCC2; -.
DR GeneID; 8494771; -.
DR KEGG; clu:CLUG_05761; -.
DR VEuPathDB; FungiDB:CLUG_05761; -.
DR HOGENOM; CLU_092107_0_0_1; -.
DR InParanoid; C4YCC2; -.
DR OMA; PKIHYPV; -.
DR OrthoDB; 1463832at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0042729; C:DASH complex; IEA:InterPro.
DR GO; GO:0072686; C:mitotic spindle; IEA:InterPro.
DR GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IEA:InterPro.
DR InterPro; IPR013962; DASH_Dam1.
DR PANTHER; PTHR28113; DASH COMPLEX SUBUNIT DAM1; 1.
DR PANTHER; PTHR28113:SF1; DASH COMPLEX SUBUNIT DAM1; 1.
DR Pfam; PF08653; DASH_Dam1; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022776};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703}.
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 113..140
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 213..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 278 AA; 31390 MW; 91743FDAB13375E7 CRC64;
MSHETYPGRR ESRRRSHRSS GIYNVMPQSP QAHYPEDVLP LETEKNIERF EAVADAVKEL
ESNMTDLAQM HAAVNGGFNE PFAAFLYGLL ITMFCNNFPG CPTQAAFESI AKVQRAQTHV
EELERRVHLL RDANKKLQDE VSSKILEQKT MAIRNEVLAR KTPARRAPLH SASRVPSLRH
RKVQVAHDDT FSTTDSFIET PAGPKHATRK PPVPRFSNST TLGQPPSDSD GPNLNQPPRY
MRGLFDKTNT SNVRRTDSKR PRPASTKNSR LASRPPFR
//
