ID C4YFJ8_CANAW Unreviewed; 794 AA.
AC C4YFJ8;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 08-NOV-2023, entry version 44.
DE RecName: Full=Inner centromere protein ARK-binding domain-containing protein {ECO:0000259|Pfam:PF03941};
GN ORFNames=CAWG_01316 {ECO:0000313|EMBL:EEQ43079.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ43079.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ43079.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ43079.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the INCENP family.
CC {ECO:0000256|ARBA:ARBA00010042}.
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DR EMBL; CH672346; EEQ43079.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YFJ8; -.
DR SMR; C4YFJ8; -.
DR PaxDb; 5476-C4YFJ8; -.
DR VEuPathDB; FungiDB:CAWG_01316; -.
DR HOGENOM; CLU_411024_0_0_1; -.
DR OMA; ANTINPH; -.
DR Proteomes; UP000001429; Chromosome 1, Supercontig 1.1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR InterPro; IPR005635; Inner_centromere_prot_ARK-bd.
DR Pfam; PF03941; INCENP_ARK-bind; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 705..757
FT /note="Inner centromere protein ARK-binding"
FT /evidence="ECO:0000259|Pfam:PF03941"
FT REGION 77..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 88765 MW; 091ED4A03D5F4332 CRC64;
MSQLWAAAAA RKRKNDYTSG SSRWVSNELN NQFMISFHSI HQFIEENQIY HESLGTLMDG
IYSGTFDPDI IRKEQVPDLT EAKSPIKETP LRPISGHLQS SQAPSSSSAV NTSKATFENT
QSHFSNLHIE YQPQPTLKPS SKDSDVVVFD KASSYNNSPN SESKDGQNRQ SDGLDDSFQA
ISKAIRKSIA GRVGDTIFKQ DLSGSDLLPN RSSSKSQYSK SDTTMQSLKS DEKSLAPKTP
KSRSSMFIAL PTREPIVIKS VSRRKSGVSK RRTMENTKSL NSDQNSVTSN TNIKSELNNT
PVSTKGEKQK FEQMSPVKLP VDKRVFREKV PMLSTGEKDD NGEKKVDKLV ERTMRKEEEH
VEHVFTLPEV EHEKPIVSVT RKVENEESVV QSTDPKDVTN DTVSPSGIWS AIGKYRSLSP
VRKPLFNSKT DDSPRSISAS TSRSRSRSRS RSPLRKEVLV HRKNSRSPRH ELFRGNSPTS
PSKLTANGGE SDLINRLTAP TSSSAAKSKS QNRKTDGRKP ERNKFLTTTL IPTTGGNNKA
KEVSPIKLKS EPYRFPKLET SSIPTLKMSM MEKRSETTLS KTRQKYIIKP TNTFKRKSEL
GKEKHEHSII PQHTHLSEDQ KLETNPQTTL GSTTQDRKSE QRIKRIKTAN GVALPEAARG
LLNKDNANKK SIASVAITPA RDEIRVGNNV LPVTPTRISP RNLPEIDSDE EGDFSKKKIL
QPWADSPILR RSIAASRSID PATVITNNPK IDLHETFQSV VSAKRGQESP AATPNMRQQE
KDMKRYFQQS GYIQ
//
