ID C4YNH5_CANAW Unreviewed; 661 AA.
AC C4YNH5;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Glycogen [starch] synthase {ECO:0000256|RuleBase:RU363104};
DE EC=2.4.1.11 {ECO:0000256|RuleBase:RU363104};
GN ORFNames=CAWG_01436 {ECO:0000313|EMBL:EEQ43208.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ43208.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ43208.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ43208.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Transfers the glycosyl residue from UDP-Glc to the non-
CC reducing end of alpha-1,4-glucan. {ECO:0000256|RuleBase:RU363104}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18550;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964, ECO:0000256|RuleBase:RU363104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010686, ECO:0000256|RuleBase:RU363104}.
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DR EMBL; CM000309; EEQ43208.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YNH5; -.
DR SMR; C4YNH5; -.
DR PaxDb; 5476-C4YNH5; -.
DR VEuPathDB; FungiDB:CAWG_01436; -.
DR HOGENOM; CLU_015910_1_0_1; -.
DR OMA; RDVRNHI; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000001429; Chromosome R.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008631; Glycogen_synth.
DR PANTHER; PTHR10176:SF3; GLYCOGEN [STARCH] SYNTHASE; 1.
DR PANTHER; PTHR10176; GLYCOGEN SYNTHASE; 1.
DR Pfam; PF05693; Glycogen_syn; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056,
KW ECO:0000256|RuleBase:RU363104};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363104};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363104}.
SQ SEQUENCE 661 AA; 75580 MW; 6D892588E976CC90 CRC64;
MARDIDNHLL FEVATEVAHK VGGIYSVLKS KAPVTVAEYR ERYTLLGPLH YDSAQIEVEE
LPVTDPHIKQ TLDSMSSKGI RWLYGRWLIE GAPRVLLFDI WSAGHYLNEW KADLWNVAGI
PTPDHDSETN DAILLGYLVA WFLGELVYND RDRAVICQCH EWLAGIALPL CRKRRIDVTT
IFTTHATLLG RYLCAGSTDF YNNLDKFDVD AEAGKRGIYH RYCIERSATH SADVFTTVSD
ITAYEAEHLL KRKPDGVLPN GLNVVKFQAV HEFQNLHAIK KAKINEFVKG HFYGNYDFDL
DNTLYFFIAG RYEFRNKGCD FFIESLARLN HKLKEAGSKT TVVAFIIMPG KTQSYTVETL
KGQAVVKQLE STIGEVQKKV GERLFEYCAR YPNTDHHGND EVPTIDELIK PADRVLLKRR
IFALKRDGLP PIVTHNMVDD STDPVLNHIR RVQLFNKPED RVKIIFHPEF LNANNPILSL
DYDEFVRGCH LGVFPSYYEP WGYTPAECTV MGIPSITTNL SGFGCYMNDL VENPTDYGIY
IVDRRMKSVD ESINQLTDYM FDFCAKSRRQ RINQRNRTER LSVLLDWRSV HSEYSKARLL
ALKRAYPDYV GEKVVESKMK ITRPMSVPGS PRSLLLTPGD LGSLQDANQD ISYFELGEEE
T
//
