ID C4YQD1_CANAW Unreviewed; 312 AA.
AC C4YQD1;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Protein CCC1 {ECO:0000313|EMBL:EEQ44420.1};
GN ORFNames=CAWG_02688 {ECO:0000313|EMBL:EEQ44420.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ44420.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ44420.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ44420.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CCC1 family.
CC {ECO:0000256|ARBA:ARBA00007049}.
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DR EMBL; CM000310; EEQ44420.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YQD1; -.
DR SMR; C4YQD1; -.
DR PaxDb; 5476-C4YQD1; -.
DR VEuPathDB; FungiDB:CAWG_02688; -.
DR HOGENOM; CLU_038957_0_0_1; -.
DR OMA; MNFHHTL; -.
DR Proteomes; UP000001429; Chromosome 3.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR CDD; cd02435; CCC1; 1.
DR InterPro; IPR008217; Ccc1_fam.
DR PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR PANTHER; PTHR31851:SF52; PROTEIN CCC1; 1.
DR Pfam; PF01988; VIT1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 312 AA; 33300 MW; 7E80FDEDFD7113D1 CRC64;
MSLVAIKNGI SKLVSSKDAS DAELERVERL IDSNQIPYGS TDSNDERAQQ LAREEAIIQA
AASISAASSS ENKEEEGVDS ITAFFNTFDP RVMSDIIIGL SDGLTVPFAL TAGLSSLGDS
KLVITGGMAE LVSGAISMGL GGYLAAKSES EYYFSQVKKE KLEFFKKPEA INQDAAEIMF
ELGASEQTII SFLKDLDAKP KNLIDFVIRY GKGLEEPAAG RELTSALTIG ASYFLGGFVP
LLPYFFTKEV GTGLIISVVA MLVVLMLFGY FKCSISMGEG CPNHKKFAAG FEMVVVGSIA
AGAAWGLVFL IE
//
