ID C4YR93_CANAW Unreviewed; 320 AA.
AC C4YR93;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Pre-rRNA-processing protein ESF2 {ECO:0000256|ARBA:ARBA00013906};
DE AltName: Full=18S rRNA factor 2 {ECO:0000256|ARBA:ARBA00032634};
DE AltName: Full=Pre-rRNA-processing protein esf2 {ECO:0000256|ARBA:ARBA00021800};
GN ORFNames=CAWG_04592 {ECO:0000313|EMBL:EEQ46246.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ46246.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ46246.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ46246.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF2/ABP1 family.
CC {ECO:0000256|ARBA:ARBA00005819}.
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DR EMBL; CM000311; EEQ46246.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YR93; -.
DR PaxDb; 5476-C4YR93; -.
DR VEuPathDB; FungiDB:CAWG_04592; -.
DR HOGENOM; CLU_054086_0_0_1; -.
DR OMA; TRKHNDF; -.
DR Proteomes; UP000001429; Chromosome 5.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd12263; RRM_ABT1_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR039119; ABT1/Esf2.
DR InterPro; IPR034353; ABT1/ESF2_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR PANTHER; PTHR12311; ACTIVATOR OF BASAL TRANSCRIPTION 1; 1.
DR PANTHER; PTHR12311:SF7; ACTIVATOR OF BASAL TRANSCRIPTION 1; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..92
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 320 AA; 36798 MW; 7287346310C1AFA9 CRC64;
MSATSDRESD FESEDENNFQ DKVFNVKSKT SSFFHANTSD NEDFSEDEED KDEQDEGDTK
TKPKDGKHNF EDIAYDEESE ENIGDDEDGN ADLSLDGGSK VNKKLKKLTS KELAKEQKRI
KRTGVCYLSR VPPYMKPAKL RSVLSRFGEI DRLFLKPEDP SVYHKRVKYG GNKKKNFTEG
WIEFVNKSDA KLCAATLNGN KLGGKKTSYY YDDIINIKYL PGFKWLDLTQ QIAKENEVRQ
AKLAMEISQQ QKLNKSFVSN VEKSKMIANI QKKRKTTDDD NIRRDFKQRK VTTTRSDAKD
DLKSKSKPTD KLNDILSKVF
//
