ID C4YSL5_CANAW Unreviewed; 465 AA.
AC C4YSL5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=CAWG_05083 {ECO:0000313|EMBL:EEQ46718.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ46718.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ46718.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ46718.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; CM000312; EEQ46718.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YSL5; -.
DR PaxDb; 5476-C4YSL5; -.
DR VEuPathDB; FungiDB:CAWG_05083; -.
DR HOGENOM; CLU_587919_0_0_1; -.
DR OMA; QGHANIE; -.
DR Proteomes; UP000001429; Chromosome 6.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09280; RNase_HI_eukaryote_like; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR Gene3D; 3.40.970.10; Ribonuclease H1, N-terminal domain; 2.
DR InterPro; IPR009027; Ribosomal_bL9/RNase_H1_N.
DR InterPro; IPR011320; RNase_H1_N.
DR InterPro; IPR037056; RNase_H1_N_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF01693; Cauli_VI; 2.
DR Pfam; PF00075; RNase_H; 2.
DR SUPFAM; SSF55658; L9 N-domain-like; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR PROSITE; PS50879; RNASE_H_1; 2.
PE 3: Inferred from homology;
FT DOMAIN 51..218
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT DOMAIN 284..451
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
SQ SEQUENCE 465 AA; 53830 MW; DF01D080E979D3C1 CRC64;
MPYYAVVNGR EEGVFSSWQD CRPHVFAYKG AHFRKFEIRN EAEEYYQNDG DYFIYPIYVD
GACRYNGCPH AEAGYGVYYG DGDSRNVSVP LDDVDPDGII PTNQRAELWA MNHALRNIWN
ELQEDTEDGK AVIYSDSIYA IKCLTKWPNK WTQNGWLNVH GQTISNYDLV TKNYELYEWI
NDEYDDRGWG ELDLIHVKGH SGNDGNEEAD NLANLAADRY GYQSSSSSSV WTIMPYYAVA
RGREVGIYSS WRECRPQVYC CKGARYRKFE NLIEAKEYCE NDGRYYIYPV YVDGACRNNG
RENAKGGYGV YYGDEDPRNV SVPLDRVDPN GIRPTNQRAE LWAMNHALKN ILNELQDETE
KGKAIIYSDS IYAINCLTKW PEKWIYNGWQ NSRGRTISNQ ELIEENYDLY ESINEEYDDR
DWGSLRFVHV KGHSGVEGNE EADRLANLAV DEYGQRSIFR SIFGF
//
